Publication: Differences in overall survival between clear cell metastatic renal cell carcinoma patients versus population-based controls according to race/ethnicity in the United States
dc.contributor.coauthor | Garcia, Cristina Cano | |
dc.contributor.coauthor | Nimer, Nancy | |
dc.contributor.coauthor | Piccinelli, Mattia Luca | |
dc.contributor.coauthor | Tappero, Stefano | |
dc.contributor.coauthor | Panunzio, Andrea | |
dc.contributor.coauthor | Barletta, Francesco | |
dc.contributor.coauthor | Incesu, Reha-Baris | |
dc.contributor.coauthor | Tian, Zhe | |
dc.contributor.coauthor | Saad, Fred | |
dc.contributor.coauthor | Kapoor, Anil | |
dc.contributor.coauthor | Briganti, Alberto | |
dc.contributor.coauthor | Terrone, Carlo | |
dc.contributor.coauthor | Shariat, Shahrokh F. | |
dc.contributor.coauthor | Antonelli, Alessandro | |
dc.contributor.coauthor | De Cobelli, Ottavio | |
dc.contributor.coauthor | Kluth, Luis A. | |
dc.contributor.coauthor | Becker, Andreas | |
dc.contributor.coauthor | Chun, Felix K. H. | |
dc.contributor.coauthor | Karakiewicz, Pierre I. | |
dc.contributor.department | KUH (Koç University Hospital) | |
dc.contributor.department | School of Medicine | |
dc.contributor.kuauthor | Tilki, Derya | |
dc.contributor.schoolcollegeinstitute | KUH (KOÇ UNIVERSITY HOSPITAL) | |
dc.contributor.schoolcollegeinstitute | SCHOOL OF MEDICINE | |
dc.date.accessioned | 2024-12-29T09:40:53Z | |
dc.date.issued | 2023 | |
dc.description.abstract | Purpose: To quantify differences in five-year overall survival (OS) between clear cell metastatic renal cell carcinoma (ccmRCC) patients and age-and sex-matched population-based controls, especially when race/ethnicity is considered. Methods: We relied on the Surveillance, Epidemiology and End Results database (2006-2016) to iden-tify newly diagnosed (2006-2011) ccmRCC patients of either Caucasian, Hispanic, African American, or Asian/Pacific Islander race/ethnicity. For each case, we simulated an age-and sex-matched control (Monte Carlo simulation), relying on Social Security Administration Life Tables with five-year follow-up. We compared OS between ccmRCC patients and controls. Multivariable Cox regression models tested for race/ethnicity effect on OS. Results: Of 3067 ccmRCC patients, 2167 (71%) were Caucasians vs. 488 (16%) Hispanics vs. 216 (7%) African Americans and 196 (6%) Asians/Pacific Islanders. At five years, OS difference between ccmRCC patients vs. population-based controls was greatest in African Americans (11 vs. 94%, A = 84%), followed by Hispanics (16 vs. 94%, A = 77%), Caucasians (16 vs. 89%, A = 73%) and Asians/Pacific Islanders (19 vs. 88%, A = 70%). In multivariable Cox regression models, African Americans exhibited highest Hazard Ratio for death (HR 1.3, p = 0.003). | |
dc.description.indexedby | WOS | |
dc.description.indexedby | Scopus | |
dc.description.indexedby | PubMed | |
dc.description.publisherscope | International | |
dc.description.sponsoredbyTubitakEu | N/A | |
dc.description.sponsorship | Cristina Cano Garcia was awarded a scholarship by the STIFTUNG GIERSCH. | |
dc.description.volume | 79 | |
dc.identifier.doi | 10.1016/j.annepidem.2023.01.003 | |
dc.identifier.eissn | 1873-2585 | |
dc.identifier.issn | 1047-2797 | |
dc.identifier.quartile | Q1 | |
dc.identifier.scopus | 2-s2.0-85146852640 | |
dc.identifier.uri | https://doi.org/10.1016/j.annepidem.2023.01.003 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14288/23476 | |
dc.identifier.wos | 991675700001 | |
dc.keywords | SEER | |
dc.keywords | Social security administration | |
dc.keywords | Metastatic renal cell carcinoma | |
dc.keywords | Life tables | |
dc.keywords | Race | |
dc.keywords | Ethnicity | |
dc.language.iso | eng | |
dc.publisher | Elsevier Science Inc | |
dc.relation.grantno | STIFTUNG GIERSCH | |
dc.relation.ispartof | Annals of Epidemiology | |
dc.subject | Public | |
dc.subject | Environmental | |
dc.subject | Occupational health | |
dc.title | Differences in overall survival between clear cell metastatic renal cell carcinoma patients versus population-based controls according to race/ethnicity in the United States | |
dc.type | Journal Article | |
dspace.entity.type | Publication | |
local.contributor.kuauthor | Tilki, Derya | |
local.publication.orgunit1 | SCHOOL OF MEDICINE | |
local.publication.orgunit1 | KUH (KOÇ UNIVERSITY HOSPITAL) | |
local.publication.orgunit2 | KUH (Koç University Hospital) | |
local.publication.orgunit2 | School of Medicine | |
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