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Sequence alignment using simulated annealing

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Güven, Can

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We apply simulated annealing to amino acid sequence alignment, a fundamental problem in bioinformatics, particularly relevant to evolution. Our goal was obtaining results comparable to those reached through dynamic programming algorithms, like the Needleman-Wunsch algorithm, as well as making a connection between physics and bioinformatics through a representative example.

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Elsevier

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Physics

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Physica A-Statistical Mechanics And Its Applications

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10.1016/j.physa.2010.02.015

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