Publication: Clinical imaging of vascular disease in chronic kidney disease
Program
KU-Authors
KU Authors
Co-Authors
Covic, Adrian
London, Gerard
Vervloet, Marc
Goldsmith, David
Luis Gorriz, Jose
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Type
Embargo Status
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Abstract
Arterial wall calcification, once considered an incidental finding, is now known to be a consistent and strong predictor of cardiovascular events in patients with chronic renal insufficiency. It is also commonly encountered in radiologic examinations as an incidental finding. Forthcoming bench, translational, and clinical data seek to establish this and pre-calcification changes as surrogate imaging biomarkers for noninvasive prognostication and treatment follow-up. Emerging paradigms seek to establish vascular calcification as a surrogate marker of disease. Imaging of pre-calcification and decalcification events may prove more important than imaging of the calcification itself. Data-driven approaches to screening will be necessary to limit radiation exposure and prevent over-utilization of expensive imaging techniques.
Source
Publisher
Springer
Subject
Urology, Nephrology
Citation
Has Part
Source
International Urology and Nephrology
Book Series Title
Edition
DOI
10.1007/s11255-016-1240-0