Publication: Rationally reprogramming single-cell aging trajectories and lifespan through dynamic modulation of environmental inputs
Program
KU-Authors
KU Authors
Co-Authors
Smart M.
Moreno DF
Publication Date
Language
Type
Embargo Status
Journal Title
Journal ISSN
Volume Title
Alternative Title
Abstract
How do variations in nutrient levels influence cellular lifespan? A dynamical systems model of a core circuit involved in yeast aging suggests principles underlying lifespan extension observed at static and alternating glucose levels that are reminiscent of intermittent fasting regimens.
Source
Publisher
Cell Press
Subject
Biochemistry and molecular biology, Cell biology
Citation
Has Part
Source
Cell Systems
Book Series Title
Edition
DOI
10.1016/j.cels.2024.07.008