Publication: Rationally reprogramming single-cell aging trajectories and lifespan through dynamic modulation of environmental inputs
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Smart, Matthew
Moreno, David F.
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Abstract
How do variations in nutrient levels influence cellular lifespan? A dynamical systems model of a core circuit involved in yeast aging suggests principles underlying lifespan extension observed at static and alternating glucose levels that are reminiscent of intermittent fasting regimens.
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Cell Press
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Cell Systems
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10.1016/j.cels.2024.07.008
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