Publication: Rationally reprogramming single-cell aging trajectories and lifespan through dynamic modulation of environmental inputs
Program
KU-Authors
KU Authors
Co-Authors
Smart M.
Moreno DF
Advisor
Publication Date
2024
Language
en
Type
Journal article
Journal Title
Journal ISSN
Volume Title
Abstract
How do variations in nutrient levels influence cellular lifespan? A dynamical systems model of a core circuit involved in yeast aging suggests principles underlying lifespan extension observed at static and alternating glucose levels that are reminiscent of intermittent fasting regimens.
Description
Source:
Cell Systems
Publisher:
Cell Press
Keywords:
Subject
Biochemistry and molecular biology, Cell biology