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Rationally reprogramming single-cell aging trajectories and lifespan through dynamic modulation of environmental inputs

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dc.contributor.coauthorSmart M.
dc.contributor.coauthorMoreno DF
dc.contributor.departmentKUTTAM (Koç University Research Center for Translational Medicine)
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorFaculty Member, Acar, Murat
dc.contributor.schoolcollegeinstituteResearch Center
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-12-29T09:36:48Z
dc.date.issued2024
dc.description.abstractHow do variations in nutrient levels influence cellular lifespan? A dynamical systems model of a core circuit involved in yeast aging suggests principles underlying lifespan extension observed at static and alternating glucose levels that are reminiscent of intermittent fasting regimens.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue8
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuTÜBİTAK
dc.description.volume15
dc.identifier.doi10.1016/j.cels.2024.07.008
dc.identifier.eissn2405-4720
dc.identifier.issn2405-4712
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-85201238812
dc.identifier.urihttps://doi.org/10.1016/j.cels.2024.07.008
dc.identifier.urihttps://hdl.handle.net/20.500.14288/22170
dc.identifier.wos1300340000001
dc.keywordsLongevity
dc.language.isoeng
dc.publisherCell Press
dc.relation.ispartofCell Systems
dc.subjectBiochemistry and molecular biology
dc.subjectCell biology
dc.titleRationally reprogramming single-cell aging trajectories and lifespan through dynamic modulation of environmental inputs
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorAcar, Murat
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit1Research Center
local.publication.orgunit2KUTTAM (Koç University Research Center for Translational Medicine)
local.publication.orgunit2School of Medicine
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