Publication:
Electro-conductive silica nanoparticles-incorporated hydrogel based on alginate as a biomimetic scaffold for bone tissue engineering application

dc.contributor.coauthorDerakhshankhah, Hossein
dc.contributor.coauthorEskandani, Morteza
dc.contributor.coauthorVandghanooni, Somayeh
dc.contributor.coauthorJaymand, Mehdi
dc.contributor.departmentDepartment of Mechanical Engineering
dc.contributor.departmentKUTTAM (Koç University Research Center for Translational Medicine)
dc.contributor.kuauthorTaşoğlu, Savaş
dc.contributor.kuauthorNakhjavani, Sattar Akbar
dc.contributor.kuprofileFaculty Member
dc.contributor.kuprofileResearcher
dc.contributor.schoolcollegeinstituteCollege of Engineering
dc.contributor.schoolcollegeinstituteResearch Center
dc.contributor.yokid291971
dc.contributor.yokidN/A
dc.date.accessioned2024-11-09T23:45:22Z
dc.date.issued2023
dc.description.abstractAn innovative electrically conductive hydrogel was fabricated through the incorporation of silica nanoparticles (SiO2 NPs) and poly(aniline-co-dopamine) (PANI-co-PDA) into oxidized alginate (OAlg) as a biomimetic scaffold for bone tissue engineering application. The developed self-healing chemical hydrogel was characterized by FTIR, SEM, TEM, XRD, and TGA. The electrical conductivity and swelling ratio of the hydrogel were obtained as 1.7 × 10−3 S cm−1 and 130%, respectively. Cytocompatibility and cell proliferation potential of the developed scaffold were approved by MTT assay using MG-63 cells. FE-SEM imaging approved the potential of the fabricated scaffold for hydroxyapatite (HA) formation and bioactivity induction through immersing in SBF solution.
dc.description.indexedbyScopus
dc.description.indexedbyWoS
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.identifier.doi10.1080/00914037.2022.2155159
dc.identifier.issn0091-4037
dc.identifier.linkhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85145744614&doi=10.1080%2f00914037.2022.2155159&partnerID=40&md5=be5883de6bab75c6c6576d707986c547
dc.identifier.quartileQ2
dc.identifier.scopus2-s2.0-85145744614
dc.identifier.urihttps://hdl.handle.net/20.500.14288/13828
dc.identifier.wos907253400001
dc.keywordsAlginate
dc.keywordsBioactivity induction
dc.keywordsBiomimetic scaffold
dc.keywordsElectrical conductivity
dc.keywordsPoly(aniline-co-dopamine)
dc.keywordsSilica nanoparticles
dc.languageEnglish
dc.publisherTaylor and Francis Ltd.
dc.sourceInternational Journal of Polymeric Materials and Polymeric Biomaterials
dc.subjectMaterials science
dc.subjectBiomedical materials
dc.subjectPolymers
dc.subjectPolymerization
dc.titleElectro-conductive silica nanoparticles-incorporated hydrogel based on alginate as a biomimetic scaffold for bone tissue engineering application
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.authorid0000-0003-4604-217X
local.contributor.authorid0000-0002-5693-350X
local.contributor.kuauthorTaşoğlu, Savaş
local.contributor.kuauthorNakhjavani, Sattar Akbar
local.publication.orgunit1College of Engineering
local.publication.orgunit1Research Center
local.publication.orgunit2Department of Mechanical Engineering
local.publication.orgunit2KUTTAM (Koç University Research Center for Translational Medicine)
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