Publication:
Application of exosomes for the alleviation of COVID-19-related pathologies

dc.contributor.coauthorRezabakhsh, Aysa
dc.contributor.coauthorMahdipour, Mahdi
dc.contributor.coauthorNourazarian, Alireza
dc.contributor.coauthorHabibollahi, Paria
dc.contributor.coauthorAvcı, Çığır Biray
dc.contributor.coauthorRahbarghazi, Reza
dc.contributor.departmentKUTTAM (Koç University Research Center for Translational Medicine)
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorSokullu, Emel
dc.contributor.schoolcollegeinstituteResearch Center
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-09T22:48:43Z
dc.date.issued2022
dc.description.abstractThe pandemic of COVID-19 caused worldwide concern. Due to the lack of appropriate medications and the inefficiency of commercially available vaccines, lots of efforts are being made to develop de novo therapeutic modalities. Besides this, the possibility of several genetic mutations in the viral genome has led to the generation of resistant strains such as Omicron against neutralizing antibodies and vaccines, leading to worsening public health status. Exosomes (Exo), nanosized vesicles, possess several therapeutic properties that participate in intercellular communication. The discovery and application of Exo in regenerative medicine have paved the way for the alleviation of several pathologies. These nanosized particles act as natural bioshuttles and transfer several biomolecules and anti-inflammatory cytokines. To date, several approaches are available for the administration of Exo into the targeted site inside the body, although the establishment of standard administration routes remains unclear. As severe acute respiratory syndrome coronavirus 2 primarily affects the respiratory system, we here tried to highlight the transplantation of Exo in the alleviation of COVID-19 pathologies.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue5
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipNational Institute for Medical Research Development (NIMAD)
dc.description.sponsorshipTabriz University of Medical Sciences
dc.description.sponsorshipNIMAD National Institute for Medical Research Development (NIMAD)
dc.description.sponsorshipTabriz University of Medical Sciences
dc.description.sponsorshipNIMAD
dc.description.volume40
dc.identifier.doi10.1002/cbf.3720
dc.identifier.eissn1099-0844
dc.identifier.issn0263-6484
dc.identifier.quartileQ3
dc.identifier.scopus2-s2.0-85131047225
dc.identifier.urihttps://doi.org/10.1002/cbf.3720
dc.identifier.urihttps://hdl.handle.net/20.500.14288/6371
dc.identifier.wos804118600001
dc.keywordsCOVID-19
dc.keywordsEosomes
dc.keywordsParacrine interaction
dc.keywordsRegenerative potential
dc.keywordsStem cell
dc.keywordsTherapeutic effects
dc.keywordsextracellular vesicles
dc.keywordsSARS-COV-2
dc.keywordsInfection
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofCell Biochemistry and Function
dc.subjectBiochemistry
dc.subjectMolecular biology
dc.subjectCell biology
dc.titleApplication of exosomes for the alleviation of COVID-19-related pathologies
dc.typeReview
dspace.entity.typePublication
local.contributor.kuauthorSokullu, Emel
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit1Research Center
local.publication.orgunit2KUTTAM (Koç University Research Center for Translational Medicine)
local.publication.orgunit2School of Medicine
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