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Role of exosomal MicroRNAs in cell-to-cell communication

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dc.contributor.coauthorTastan, Bora
dc.contributor.coauthorTarakcioglu, Emre
dc.contributor.coauthorGenc, Sermin
dc.contributor.departmentDepartment of Molecular Biology and Genetics
dc.contributor.kuauthorBirinci, Yelda
dc.contributor.kuauthorPark, Yongsoo
dc.contributor.schoolcollegeinstituteCollege of Sciences
dc.date.accessioned2024-11-09T23:49:38Z
dc.date.issued2022
dc.description.abstractExosomes, a type of extracellular vesicle, are small vesicles (30–100 nm) secreted into extracellular space from almost all types of cells. Exosomes mediate cell-to-cell communication carrying various biologically active molecules including microRNAs. Studies have shown that exosomal microRNAs play fundamental roles in healthy and pathological conditions such as immunity, cancer, and inflammation. In this chapter, we introduce the current knowledge on exosome biogenesis, techniques used in exosome research, and exosomal miRNA and their functions in biological and pathological processes.
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.openaccessYES
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume2257
dc.identifier.doi10.1007/978-1-0716-1170-8_14
dc.identifier.issn1064-3745
dc.identifier.scopus2-s2.0-85114112213
dc.identifier.urihttps://doi.org/10.1007/978-1-0716-1170-8_14
dc.identifier.urihttps://hdl.handle.net/20.500.14288/14405
dc.keywordsCancer
dc.keywordsCardiovascular system
dc.keywordsCentral nervous system
dc.keywordsExosome
dc.keywordsImmune system
dc.keywordsInflammation
dc.keywordsMicroRNA biological marker
dc.keywordsMicroRNA
dc.keywordsmicroRNA
dc.keywordsAnalytic method
dc.keywordsBiogenesis
dc.keywordsCardiac muscle cell
dc.keywordsCardiovascular system
dc.keywordsCell communication
dc.keywordsCell isolation
dc.keywordsCell size
dc.keywordsCellular immunity
dc.keywordsCellular secretion
dc.keywordsCentral nervous system
dc.keywordsDifferential ultracentrifugation
dc.keywordsEndothelium cell
dc.keywordsExosome
dc.keywordsFibroblast
dc.keywordsGene function
dc.keywordsHuman
dc.keywordsImmunoaffinity capturebased method
dc.keywordsImmunocompetent cell
dc.keywordsInflammation
dc.keywordsMalignant neoplasm
dc.keywordsNonhuman
dc.keywordsPrecipitation
dc.keywordsStem cell
dc.keywordsUltracentrifugation
dc.keywordsGenetics
dc.keywordsNeoplasm
dc.keywordsCell communication
dc.keywordsExosomes
dc.keywordsExtracellular vesicles
dc.keywordsHumans
dc.keywordsMicroRNAs
dc.keywordsNeoplasms
dc.language.isoeng
dc.publisherHumana Press Inc.
dc.relation.ispartofMethods in Molecular Biology
dc.subjectExosomes
dc.subjectExtracellular vesicles
dc.subjectMicrorna
dc.titleRole of exosomal MicroRNAs in cell-to-cell communication
dc.typeBook Chapter
dspace.entity.typePublication
local.contributor.kuauthorPark, Yongsoo
local.contributor.kuauthorBirinci, Yelda
local.publication.orgunit1College of Sciences
local.publication.orgunit2Department of Molecular Biology and Genetics
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relation.isOrgUnitOfPublication.latestForDiscoveryaee2d329-aabe-4b58-ba67-09dbf8575547
relation.isParentOrgUnitOfPublicationaf0395b0-7219-4165-a909-7016fa30932d
relation.isParentOrgUnitOfPublication.latestForDiscoveryaf0395b0-7219-4165-a909-7016fa30932d

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