Publication: Complications of metabolic acidosis and alkalinizing therapy in chronic kidney disease patients: a clinician-directed organ-specific primer
Program
KU-Authors
KU Authors
Co-Authors
Sag, Alan A.
Afsar, Baris
Rossignol, Patrick
Covic, Adrian
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Abstract
Chronic kidney disease is prevalent, affecting more than one in ten adults. In this population, metabolic acidosis is considered a key underlying pathophysiological feature, tying together bone mineral disorders, sarcopenia, insulin resistance, vascular calcification, pro-inflammatory and pro-thrombotic states. This review aims to address the paucity of literature on alkalinizing agents, a promising treatment option that has known adverse effects
Source
Publisher
Springer
Subject
Urology, Nephrology
Citation
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Source
International Urology and Nephrology
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DOI
10.1007/s11255-020-02563-2
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