Primary cutaneous CD4+small/medium T-cell lymphoproliferative disorder: a case with multiple tumors

Abstract

Dear Editor, Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder (PCSM-TCLPD) is defined to be 6% of primary cutaneous lymphomas.1 Although it is considered to have an uncertain malignant potential, it has almost always a benign prognosis with locally limited indolent tumors. Due to the benign biological behavior, World Health Organization’s working group renamed and classified this entity as a lymphoproliferative disorder in 2016, and it was suggested to no longer diagnose this provisional entity as an overt lymphoma.