Publication: Changing trends in the etiology of liver transplantation in Turkiye: a multicenter study
dc.contributor.coauthor | Akarsu, Mesut | |
dc.contributor.coauthor | Dolu, Süleyman | |
dc.contributor.coauthor | Harputluoğlu, Murat | |
dc.contributor.coauthor | Yılmaz, Sezai | |
dc.contributor.coauthor | Polat, Kamil Yalçın | |
dc.contributor.coauthor | Dinçer, Dinç | |
dc.contributor.coauthor | Adanır, Haydar | |
dc.contributor.coauthor | Turan, İlker | |
dc.contributor.coauthor | Günsar, Fulya | |
dc.contributor.coauthor | Karasu, Zeki | |
dc.contributor.coauthor | Gökcan, Hale | |
dc.contributor.coauthor | Karademir, Sedat | |
dc.contributor.coauthor | Kabacam, Gökhan | |
dc.contributor.coauthor | Kayhan, Meral Akdoğan | |
dc.contributor.coauthor | Kıyıcı, Murat | |
dc.contributor.coauthor | Gülşen, Murat Taner | |
dc.contributor.coauthor | Balaban, Yasemin | |
dc.contributor.coauthor | Doğrul, Ahmet Bülent | |
dc.contributor.coauthor | Senkaya, Ali | |
dc.contributor.coauthor | Ellik, Zeynep Melekoğlu | |
dc.contributor.coauthor | Eren, Fatih | |
dc.contributor.coauthor | İdilman, Ramazan | |
dc.contributor.department | KUH (Koç University Hospital) | |
dc.contributor.department | School of Medicine | |
dc.contributor.kuauthor | Akyıldız, Murat | |
dc.contributor.kuauthor | Gençdal, Genco | |
dc.contributor.schoolcollegeinstitute | KUH (KOÇ UNIVERSITY HOSPITAL) | |
dc.contributor.schoolcollegeinstitute | SCHOOL OF MEDICINE | |
dc.date.accessioned | 2024-12-29T09:37:38Z | |
dc.date.issued | 2024 | |
dc.description.abstract | Background and aim: This study aimed to identify the indications for liver transplantation (LT) based on underlying etiology and to characterize the patients who underwent LT. Materials and methods: We conducted a multicenter cross-sectional observational study across 11 tertiary centers in Turkiye from 2010 to 2020. The study included 5,080 adult patients. Results: The mean age of patients was 50.3 +/- 15.2 years, with a predominance of female patients (70%). Chronic viral hepatitis (46%) was the leading etiological factor, with Hepatitis B virus infection at 35%, followed by cryptogenic cirrhosis (24%), Hepatitis C virus infection (8%), and alcohol-related liver disease (ALD) (6%). Post-2015, there was a significant increase in both the number of liver transplants and the proportion of living donor liver transplants (p<0.001). A comparative analysis of patient characteristics before and after 2015 showed a significant decline in viral hepatitis-related LT (p<0.001), whereas fatty liver disease-related LT significantly increased (p<0.001). Conclusion: Chronic viral hepatitis continues to be the primary indication for LT in Turkiye. However, the proportions of non-alcoholic fatty liver disease (NAFLD) and ALD-related LT have seen an upward trend over the years. | |
dc.description.indexedby | WOS | |
dc.description.indexedby | Scopus | |
dc.description.indexedby | PubMed | |
dc.description.indexedby | TR Dizin | |
dc.description.issue | 1 | |
dc.description.openaccess | Bronze, Green Published | |
dc.description.publisherscope | National | |
dc.description.sponsoredbyTubitakEu | N/A | |
dc.description.volume | 5 | |
dc.identifier.doi | 10.14744/hf.2023.2023.0010 | |
dc.identifier.eissn | 2757-7392 | |
dc.identifier.issn | 1307-5888 | |
dc.identifier.quartile | Q4 | |
dc.identifier.scopus | 2-s2.0-85183838612 | |
dc.identifier.uri | https://doi.org/10.14744/hf.2023.2023.0010 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14288/22434 | |
dc.identifier.wos | 1163820300009 | |
dc.keywords | Etiology | |
dc.keywords | HBV | |
dc.keywords | NAFLD | |
dc.keywords | Liver transplantation | |
dc.language.iso | eng | |
dc.publisher | Kare Publ | |
dc.relation.ispartof | Hepatology Forum | |
dc.subject | Gastroenterology and hepatology | |
dc.title | Changing trends in the etiology of liver transplantation in Turkiye: a multicenter study | |
dc.type | Journal Article | |
dspace.entity.type | Publication | |
local.contributor.kuauthor | Akyıldız, Murat | |
local.contributor.kuauthor | Gençdal, Genco | |
local.publication.orgunit1 | SCHOOL OF MEDICINE | |
local.publication.orgunit1 | KUH (KOÇ UNIVERSITY HOSPITAL) | |
local.publication.orgunit2 | KUH (Koç University Hospital) | |
local.publication.orgunit2 | School of Medicine | |
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relation.isOrgUnitOfPublication | d02929e1-2a70-44f0-ae17-7819f587bedd | |
relation.isOrgUnitOfPublication.latestForDiscovery | f91d21f0-6b13-46ce-939a-db68e4c8d2ab | |
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relation.isParentOrgUnitOfPublication | 17f2dc8e-6e54-4fa8-b5e0-d6415123a93e | |
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