Publication: Thromboembolic complications after COVID-19 in kidney transplant recipients
Program
School / College / Institute
GRADUATE SCHOOL OF HEALTH SCIENCES
Research Center
Research Center
KU-Authors
KU Authors
Co-Authors
Artan, Ayse Serra
Dirim, Ahmet Burak
Yavuzkilic, Halil
Oto, Ozgur Akin
Guller, Nurana
Safak, Seda
Yazici, Halil
Turkmen, Aydin
Publication Date
Language
Type
Embargo Status
Journal Title
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Volume Title
Alternative Title
Abstract
Aim: Increased venous thrombosis and arterial embolism rates are observed in the general population during or after COVID-19. Data regarding the kidney transplant population are scarce. In this study, we aim to investigate the thrombotic complications and risk factors associated with thrombotic complications in kidney transplant patients.Methods: This retrospective observational study included adult kidney transplant recipients diagnosed with COVID-19 between March 2020 and June 2022. The endpoint was the occurrence of thromboembolic events.Results: Four hundred and sixty-nine patients were followed for a median of 10.8 months after COVID-19. Forty patients (8.5%) died. Thromboembolic complications developed in 51 (11.9%) of the surviving patients. Twenty-four patients with thromboembolic events were receiving prophylactic anticoagulation before the event. The patients with mild, moderate, and severe COVID-19 were 292, 129, and 48, respectively. Patients with moderate COVID-19 had a significantly higher percentage of thromboembolic complications than patients with mild COVID-19. Older age, prior heart disease, and moderate COVID-19 were significantly associated with thromboembolic events. The incidence of thromboembolic events after COVID-19 is 10.9 per 100 patient-year.Conclusion: Thromboembolic complications were observed at increased rates in kidney transplant recipients after COVID-19. Therefore, prospective and cohort studies for post-COVID-19 complications regarding the treatment modalities are urgently needed.
Source
Publisher
Wiley
Subject
Urology and nephrology
Citation
Has Part
Source
Nephrology
Book Series Title
Edition
DOI
10.1111/nep.14242