Publication:
CT and 18F- FDG-PET-CT findings in secondary adrenal lymphoma with pathologic correlation

dc.contributor.coauthorÜçışık-Keser, Fehime Eymen
dc.contributor.coauthorMedeiros, L. Jeffrey
dc.contributor.coauthorNg, Chaan Sş
dc.contributor.departmentKUH (Koç University Hospital)
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorAltınmakas, Emre
dc.contributor.schoolcollegeinstituteKUH (KOÇ UNIVERSITY HOSPITAL)
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-09T23:58:02Z
dc.date.issued2019
dc.description.abstractRationale and Objective: To evaluate computed tomography (CT) and positron emission tomography-computed tomography (PET-CD imaging manifestations of lymphomas secondarily involving the adrenal gland. Materials and Methods: Seven patients (Five men, two women; median age [range], 66 years [34-75 years]) with pathologically proven adrenal lymphoma were assessed retrospectively. Clinical findings, prior history of lymphoproliferative malignancy, CT (n = 7) and fludeoxyglucose positron emission tomography-computed tomography (F-18-FDG-PET-CT) (n = 6) features were analyzed. Results: Six cases were diffuse large B-cell lymphoma, and one case was peripheral T-cell lymphoma. The longest diameter of the lesions ranged from 3.2 to 6.6 cm (median 4.3 cm). Six lesions were well-defined and one lesion was ill-defined. In five cases, an adreniform shape was preserved. No lesions contained fat, calcification or hemorrhage. Two lesions had necrosis on CT. Median (range) unenhanced CT density of six lesions was 31.8 (29.2-35.2) Hounsfield units. Following administration of IV contrast media (n = 6), three lesions enhanced homogenously whereas three enhanced heterogeneously. The median increase in attenuation was 35.1 Hounsfield units. Two patients had 15-minute delayed CT and they both demonstrated limited wash-out consistent with nonadenoma. Six patients had fludeoxyglucose positron emission tomography-computed tomography(F-18-FDG-PET-CT) and all lesions were fludeoxyglucose (FDG) avid with a median SUV(max )of 18.6 (range: 10.3-49.2). Conclusion: Secondary adrenal lymphomas usually manifest as, large (>3 cm), well-defined, homogenously or slightly heterogeneously enhancing masses on CT with preserved adreniform shape. These lesions tend to show limited wash-out and high fludeoxyglucose (FDG) uptake.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue6
dc.description.openaccessNO
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume26
dc.identifier.doi10.1016/j.acra.2018.06.025
dc.identifier.eissn1878-4046
dc.identifier.issn1076-6332
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-85050666418
dc.identifier.urihttps://doi.org/10.1016/j.acra.2018.06.025
dc.identifier.urihttps://hdl.handle.net/20.500.14288/15379
dc.identifier.wos613330900001
dc.keywordsAdrenal
dc.keywordsSecondary adrenal iymphoma
dc.keywordsCT
dc.keywordsF-18-FDG-PET-CT
dc.language.isoeng
dc.publisherElsevier Science Inc
dc.relation.ispartofAcademic Radiology
dc.subjectRadiology
dc.subjectNuclear medicine
dc.subjectMedical imaging
dc.titleCT and 18F- FDG-PET-CT findings in secondary adrenal lymphoma with pathologic correlation
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorAltınmakas, Emre
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit1KUH (KOÇ UNIVERSITY HOSPITAL)
local.publication.orgunit2KUH (Koç University Hospital)
local.publication.orgunit2School of Medicine
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