Non-invasive treatment of pterygopalatine fossa schwannoma with Gamma Knife radiosurgery

Abstract

Background: Surgical resection for pterygopalatine fossa schwannomas (PFS) can be challenging due to the complex anatomy and potential morbidity. Gamma Knife radiosurgery (GKRS) offers a minimally invasive alternative with precise targeting and minimal damage to surrounding structures. Case report: A 21-year-old female patient who had a history of progressive left-sided facial numbness over the past year and was diagnosed with progressive PFS underwent GKRS. The radiological and clinical outcomes of the patient were evaluated over a period of 15 years, with the patient remaining symptom-free and experiencing no adverse effects from the treatment. Conclusion: The patient's positive outcome, with significant tumor reduction and symptom relief, underscores the potential of this non-invasive technique as a primary treatment modality for schwannomas in challenging anatomical locations.