Publication: Acute kidney injury in hospitalized COVID-19 patients
dc.contributor.coauthor | Medetalibeyoğlu, Alpay | |
dc.contributor.coauthor | Kanbay, Asiye | |
dc.contributor.coauthor | Naci | |
dc.contributor.coauthor | Konyaoğlu, Hilal | |
dc.contributor.coauthor | Akpınar, Timur S. | |
dc.contributor.coauthor | Köse, Murat | |
dc.contributor.coauthor | Covic, Adrian | |
dc.contributor.coauthor | Tükek, Tufan | |
dc.contributor.department | KUTTAM (Koç University Research Center for Translational Medicine) | |
dc.contributor.department | School of Medicine | |
dc.contributor.kuauthor | Baygül, Arzu Eden | |
dc.contributor.kuauthor | Çevik, Enes | |
dc.contributor.kuauthor | Kanbay, Mehmet | |
dc.contributor.kuauthor | Tanrıöver, Cem | |
dc.contributor.schoolcollegeinstitute | Research Center | |
dc.contributor.schoolcollegeinstitute | SCHOOL OF MEDICINE | |
dc.date.accessioned | 2024-11-09T23:29:43Z | |
dc.date.issued | 2022 | |
dc.description.abstract | Background: Acute kidney injury (AKI) in COVID-19 patients is associated with poor prognosis. However, the incidence, risk factors and potential outcomes of AKI in hospitalized patients are not well studied. Materials and methods: This is a retrospective cohort study conducted in two major university hospitals. Electronic health records of the patients, 18 years or older, hospitalized between 13 April and 1 June 2020 with confirmed COVID-19 were reviewed. We described the incidence and the risk factors for AKI development in COVID-19 patients. Furthermore, we investigated the effects of AKI on the length of hospital and intensive care unit (ICU) stay, the admission rates to ICU, the percentage of patients with cytokine storm and in-hospital mortality rate. Results: Among 770 hospitalized patients included in this study, 92 (11.9%) patients developed AKI. The length of hospitalized days (16 vs 9.9, p < 0.001) and days spent in the hospital until ICU admission (3.5 vs. 2.5, p = 0.003) were higher in the AKI group compared to patients without AKI. In addition, ICU admission rates were also significantly higher in patients with AKI (63% vs. 20.7%, p < 0.001). The percentage of patients with AKI who developed cytokine storm was significantly higher than patients without AKI (25.9% vs. 14%, p = 0.009). Furthermore, the in-hospital mortality rate was significantly higher in patients with AKI (47.2% vs. 4.7%, p < 0.001). Conclusions: AKI is common in hospitalized COVID-19 patients. Furthermore, we show that AKI increases the admission rates to ICU and in-hospital mortality. Our findings suggest that AKI should be effectively managed to prevent the adverse outcomes in COVID-19 patients. | |
dc.description.indexedby | WOS | |
dc.description.indexedby | Scopus | |
dc.description.issue | 5 | |
dc.description.openaccess | NO | |
dc.description.publisherscope | International | |
dc.description.sponsoredbyTubitakEu | N/A | |
dc.description.volume | 54 | |
dc.identifier.doi | 10.1007/s11255-021-02972-x | |
dc.identifier.eissn | 1573-2584 | |
dc.identifier.issn | 0301-1623 | |
dc.identifier.quartile | Q3 | |
dc.identifier.scopus | 2-s2.0-85112808078 | |
dc.identifier.uri | https://doi.org/10.1007/s11255-021-02972-x | |
dc.identifier.uri | https://hdl.handle.net/20.500.14288/12107 | |
dc.identifier.wos | 686476100001 | |
dc.keywords | COVID-19 | |
dc.keywords | Acute kidney injury | |
dc.keywords | Hospital stay | |
dc.keywords | Mortality | |
dc.language.iso | eng | |
dc.relation.ispartof | International Urology and Nephrology | |
dc.subject | Urology | |
dc.subject | Nephrology | |
dc.title | Acute kidney injury in hospitalized COVID-19 patients | |
dc.type | Journal Article | |
dspace.entity.type | Publication | |
local.contributor.kuauthor | Kanbay, Mehmet | |
local.contributor.kuauthor | Çevik, Enes | |
local.contributor.kuauthor | Tanrıöver, Cem | |
local.contributor.kuauthor | Baygül, Arzu Eden | |
local.publication.orgunit1 | SCHOOL OF MEDICINE | |
local.publication.orgunit1 | Research Center | |
local.publication.orgunit2 | KUTTAM (Koç University Research Center for Translational Medicine) | |
local.publication.orgunit2 | School of Medicine | |
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