Publication:
Fabrication of gold nanoflower-coated photosensitive meta-structures using PμSL 3D printing for hyperthermia applications

dc.contributor.coauthorErsoy, Serra
dc.contributor.coauthorYıldız, Erdost
dc.contributor.coauthorRen, Ziyu
dc.contributor.coauthorZhang, Mingchao
dc.contributor.coauthorZhang, Hongchuan
dc.contributor.coauthorShiva, Anitha
dc.contributor.coauthorYunusa, Muhammed
dc.contributor.coauthorKaya, Cengiz
dc.contributor.coauthorKoç, Bahattin
dc.contributor.departmentDepartment of Mechanical Engineering
dc.contributor.departmentGraduate School of Sciences and Engineering
dc.contributor.kuauthorHan, Mertcan
dc.contributor.kuauthorKaraz, Selcan
dc.contributor.kuauthorSitti, Metin
dc.contributor.schoolcollegeinstituteCollege of Engineering
dc.contributor.schoolcollegeinstituteGRADUATE SCHOOL OF SCIENCES AND ENGINEERING
dc.date.accessioned2024-12-29T09:36:04Z
dc.date.issued2024
dc.description.abstractThe objective of this work was to print nanoparticle-added photothermoresponsive hydrogels to remove the drawbacks of photothermal therapy (PTT), which is a substitute for conventional cancer treatment. For printing hydrogels (LIHAM) via N-isopropylacrylamide (NIPAM), polyethylene glycol, green synthesized gold nanoflowers (AuNPs) coated with rose bengal (RB) as a photosensitizer, and polydopamine (PDA) as photoinitiator material were used. The printing procedure for the meta-structure, which was designed as 20 × 2 mm using the 3DS Max Autodesk Software, was carried out with the microArch S240 BMF PμSL 3D printer. Additionally, the intensity of light was 60 lm, and the exposure printer time was 8-6-6-6-4 s for this research article. Five different photosensitive hydrogels were printed for rheological measurements, Fourier-transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, differential scanning calorimetry, and hyperthermia analysis. This study also aims to demonstrate that the kirigami LIHAM hydrogel can change shape by doping with AuNPs@PDA@RB exclusively under 565 nm without the need for a heater. The results indicated that the greatest outcomes in terms of mechanical, rheological, chemical, and thermal properties and printability were obtained with LIHAM hydrogels coated with AuNPs@PDA@RB. As a result, it has been seen that the LIHAM hydrogels coated with green synthesized gold nanoflowers can be produced with a 3D printer in microsized and complex structures and can be used in hyperthermia applications in the future. © 2024 American Chemical Society.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.issue17
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume6
dc.identifier.doi10.1021/acsapm.4c01951
dc.identifier.issn2637-6105
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-85202943830
dc.identifier.urihttps://doi.org/10.1021/acsapm.4c01951
dc.identifier.urihttps://hdl.handle.net/20.500.14288/21930
dc.identifier.wos1304096500001
dc.keywordsGreen synthesis
dc.keywordsKirigami
dc.keywordsPolydopamine
dc.keywordsRose bengal
dc.keywordsTransition metal nanoparticles
dc.language.isoeng
dc.publisherAmerican Chemical Society
dc.relation.ispartofACS Applied Polymer Materials
dc.subjectNanoparticle
dc.subjectAntiinfective agent
dc.subjectTransmission electron microscopy
dc.titleFabrication of gold nanoflower-coated photosensitive meta-structures using PμSL 3D printing for hyperthermia applications
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorKaraz, Selcan
local.contributor.kuauthorHan, Mertcan
local.contributor.kuauthorSitti, Metin
local.publication.orgunit1GRADUATE SCHOOL OF SCIENCES AND ENGINEERING
local.publication.orgunit1College of Engineering
local.publication.orgunit2Department of Mechanical Engineering
local.publication.orgunit2Graduate School of Sciences and Engineering
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