Publication:
A novel ultra-low 6-month PSA cutoff for radiographic PFS stratification in high-volume mHSPC.

Simple item page
dc.conference.dateMAY 29-JUN 02, 2026
dc.conference.locationChicago, IL
dc.contributor.coauthorKapar, C.
dc.contributor.departmentSchool of Medicine
dc.contributor.departmentKUH (Koç University Hospital)
dc.contributor.kuauthorKemik, Fatih
dc.contributor.kuauthorKıkılı, Cevat İlteriş
dc.contributor.kuauthorEsen, Buğra Han
dc.contributor.kuauthorKöylü, Bahadır
dc.contributor.kuauthorBeyhan, İbrahim
dc.contributor.kuauthorSelçukbiricik, Fatih
dc.contributor.kuauthorTural, Deniz
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.contributor.schoolcollegeinstituteKUH (KOÇ UNIVERSITY HOSPITAL)
dc.date.accessioned2026-07-19T19:48:16Z
dc.date.issued2026
dc.description.abstractIn metastatic hormone-sensitive prostate cancer (mHSPC), a 6-month PSA nadir ≤0.2 ng/mL is commonly applied as an early prognostic benchmark. Moreover, routine PSA reporting is often truncated at low values (e.g., 0.07 ng/mL was associated with higher risk of radiographic progression (HR 14.27; 95% CI 3.51–58.05; p 0.07 ng/mL identifies a population at imminent risk of radiographic progression. This deeper PSA response provides a pragmatic candidate threshold for assessing treatment efficacy and for risk stratification in high-volume disease, warranting validation in larger, well-designed studies.
dc.description.harvestedfromManual
dc.description.indexedbyWOS
dc.description.publisherscopeInternational
dc.description.readpublishN/A
dc.description.sponsoredbyTubitakEuN/A
dc.description.versionPublished Version
dc.identifier.ScopusPercentile92
dc.identifier.ScopusQuartileQ1
dc.identifier.WoSPercentile98.0
dc.identifier.WoSQuartileQ1
dc.identifier.doi10.1200/jco.2026.44.16_suppl.e17099
dc.identifier.eissn1527-7755
dc.identifier.embargoN/A
dc.identifier.issn0732-183X
dc.identifier.urihttp://doi.org/10.1200/jco.2026.44.16_suppl.e17099
dc.identifier.urihttps://hdl.handle.net/20.500.14288/33526
dc.identifier.volume44
dc.identifier.wos001780492900008
dc.keywordsProstate cancer
dc.keywordsCutoff
dc.keywordsRisk stratification
dc.keywordsProportional hazards model
dc.keywordsLimiting
dc.keywordsHazard ratio
dc.keywordsProstate-specific antigen
dc.keywordsReceiver operating characteristic
dc.languageeng
dc.publisherAmerican Society of Clinical Oncology
dc.relation.affiliationKoç University
dc.relation.collectionKoç University Institutional Repository
dc.relation.ispartofJournal of Clinical Oncology
dc.relation.openaccessN/A
dc.rightsN/A
dc.rights.uriN/A
dc.subjectHealth sciences
dc.subjectMedicine
dc.subjectOncology
dc.titleA novel ultra-low 6-month PSA cutoff for radiographic PFS stratification in high-volume mHSPC.
dc.typeJournal Article
dspace.entity.typePublication
relation.isOrgUnitOfPublicationd02929e1-2a70-44f0-ae17-7819f587bedd
relation.isOrgUnitOfPublicationf91d21f0-6b13-46ce-939a-db68e4c8d2ab
relation.isOrgUnitOfPublication.latestForDiscoveryd02929e1-2a70-44f0-ae17-7819f587bedd
relation.isParentOrgUnitOfPublication17f2dc8e-6e54-4fa8-b5e0-d6415123a93e
relation.isParentOrgUnitOfPublication055775c9-9efe-43ec-814f-f6d771fa6dee
relation.isParentOrgUnitOfPublication.latestForDiscovery17f2dc8e-6e54-4fa8-b5e0-d6415123a93e

Files

Collections

Publications without Fulltext