Publication: Characteristics of newly diagnosed hepatocellular carcinoma patients across Turkey: prospective multicenter observational 3K registry study
dc.contributor.coauthor | Akarca, Ulus Salih | |
dc.contributor.coauthor | Ünsal, Belkıs | |
dc.contributor.coauthor | Sezgin, Orhan | |
dc.contributor.coauthor | Yalçın, Kendal | |
dc.contributor.coauthor | Akdoğan, Meral | |
dc.contributor.coauthor | Gönen, Can | |
dc.contributor.coauthor | Gündüz, Feyza | |
dc.contributor.coauthor | Özenirler, Seren | |
dc.contributor.coauthor | Sonsuz, Abdullah | |
dc.contributor.coauthor | Dinçer, Dinç | |
dc.contributor.coauthor | Tekin, Salim Başol | |
dc.contributor.coauthor | Yücel, İdris | |
dc.contributor.coauthor | Akbulut, Hakan | |
dc.contributor.coauthor | Alkım, Canan | |
dc.contributor.coauthor | Özyılkan, Özgür | |
dc.contributor.coauthor | Çevik, Zeynep Merve | |
dc.contributor.coauthor | İdilman, Ramazan | |
dc.contributor.coauthor | 3K Registry Study Group | |
dc.contributor.department | School of Medicine | |
dc.contributor.kuauthor | Baygül, Arzu Eden | |
dc.contributor.schoolcollegeinstitute | SCHOOL OF MEDICINE | |
dc.date.accessioned | 2024-11-09T13:11:59Z | |
dc.date.issued | 2021 | |
dc.description.abstract | Aims: to evaluate patient profile for epidemiological and clinicopathological characteristics and potential risk/prognostic factors in newly diagnosed hepatocellular carcinoma (HCC) patients across Turkey. Methods: a total of 547 patients (mean (SD) age 62.6 (10.3) years, 81.9% were males) were included in this registry study. Data on patient characteristics, etiologies of HCC, laboratory values, and tumor characteristics and stages were recorded at study enrollment. Results: HBV infection (68.2%) was the leading etiology, followed by HCV infection (17.2%), HDV infection (5.5%), alcohol (6.4%), and NAFLD (3.5%), as the major etiologies. Considering that 51.6% of the patients had >5 cm HCC, 44% were Child-Pugh B/C and 57% were BCLC B-D, it appears that a significant group of HCC patients were diagnosed at advanced stages. Of 540 patients, 271 (50.2%) were referred or applied with the diagnosis of HCC. Patients with HCC at presentation had larger tumor size (median (min-max) 6.6 (0-30) vs. 4.8 (0-90) cm, P<.001) and more advanced BCLC stage (Stage C-D in 40.8% vs. 26.4%, respectively, P=.005), compared to patients who were diagnosed during follow-up. Conclusions: our findings revealed that HBV infection was the leading etiology and a moderate-to-advanced disease was evident in more than half of patients at the time of diagnosis. HCC patients diagnosed at follow-up had smaller tumor size and earlier BCLC stage. | |
dc.description.fulltext | YES | |
dc.description.indexedby | WOS | |
dc.description.indexedby | Scopus | |
dc.description.indexedby | PubMed | |
dc.description.issue | 12 | |
dc.description.openaccess | YES | |
dc.description.publisherscope | National | |
dc.description.sponsoredbyTubitakEu | N/A | |
dc.description.sponsorship | Bayer Türk | |
dc.description.version | Publisher version | |
dc.description.volume | 32 | |
dc.identifier.doi | 10.5152/tjg.2021.201171 | |
dc.identifier.eissn | 2148-5607 | |
dc.identifier.embargo | NO | |
dc.identifier.filenameinventoryno | IR03373 | |
dc.identifier.issn | 1300-4948 | |
dc.identifier.quartile | Q4 | |
dc.identifier.scopus | 2-s2.0-85122498900 | |
dc.identifier.uri | https://doi.org/10.5152/tjg.2021.201171 | |
dc.identifier.wos | 727747700004 | |
dc.keywords | Hepatocellular carcinoma | |
dc.keywords | Epidemiology | |
dc.keywords | Risk factors | |
dc.keywords | Prognostic factors | |
dc.keywords | Screening | |
dc.keywords | Turkey | |
dc.language.iso | eng | |
dc.publisher | Aves | |
dc.relation.grantno | NA | |
dc.relation.ispartof | Turkish Journal of Gastroenterology | |
dc.relation.uri | http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/10158 | |
dc.subject | Gastroenterology and hepatology | |
dc.title | Characteristics of newly diagnosed hepatocellular carcinoma patients across Turkey: prospective multicenter observational 3K registry study | |
dc.type | Journal Article | |
dspace.entity.type | Publication | |
local.contributor.kuauthor | Baygül, Arzu Eden | |
local.publication.orgunit1 | SCHOOL OF MEDICINE | |
local.publication.orgunit2 | School of Medicine | |
relation.isOrgUnitOfPublication | d02929e1-2a70-44f0-ae17-7819f587bedd | |
relation.isOrgUnitOfPublication.latestForDiscovery | d02929e1-2a70-44f0-ae17-7819f587bedd | |
relation.isParentOrgUnitOfPublication | 17f2dc8e-6e54-4fa8-b5e0-d6415123a93e | |
relation.isParentOrgUnitOfPublication.latestForDiscovery | 17f2dc8e-6e54-4fa8-b5e0-d6415123a93e |
Files
Original bundle
1 - 1 of 1