Publication:
Impact of rehabilitation on fatigue in post-Covid-19 patients: a systematic review and meta-analysis

dc.contributor.coauthorde Sire, Alessandro
dc.contributor.coauthorMoggio, Lucrezia
dc.contributor.coauthorMarotta, Nicola
dc.contributor.coauthorAgostini, Francesco
dc.contributor.coauthorTasselli, Anna
dc.contributor.coauthorFerrante, Vera Drago
dc.contributor.coauthorCurci, Claudio
dc.contributor.coauthorCalafiore, Dario
dc.contributor.coauthorFerraro, Francesco
dc.contributor.coauthorBernetti, Andrea
dc.contributor.coauthorAmmendolia, Antonio
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorTaşkıran, Özden Özyemişçi
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-09T13:45:56Z
dc.date.issued2022
dc.description.abstractThe post-COVID-19 syndrome may affect patients after the COVID-19 post-acute phase. In particular, the 69% of patients reported persistent fatigue at the discharge. To date, no clear data are available regarding the most effective rehabilitative approaches for the treatment of this condition. Thus, this systematic review aimed to evaluate the rehabilitation treatment's efficacy on fatigue in post-COVID-19 patients. We systematically searched PubMed, Scopus, and Web of Science databases to find longitudinal study designs presenting: post-COVID-19 patients as participants; a rehabilitative approach aimed to reduce post-COVID-19 syndrome as intervention; and fatigue intensity assessed through an evaluation tool that quantified the perceived exertion (i.e., fatigue severity scale, FSS; Borg Scale (BS); Borg Category Ratio 10, CR10; Checklist Individual Strength (CIS) fatigue scale; FACIT (Functional Assessment of Chronic Illness Therapy) fatigue scale). The present systematic review protocol was registered on PROSPERO (registration number CRD42021284058). Out of 704 articles, 6 studies were included. Nearly all patients showed COVID-19-related fatigue, and after the rehabilitation treatment, only 17% of subjects reported the persistency of symptoms. The overall effect size reported a -1.40 decrease in Borg Category Ratio 10 with a SE of 0.05 and a 95% CI between -1.50 and -1.30 (p < 0.001). The present systematic review and meta-analysis underlines the rehabilitation role in the fatigue reduction in patients affected by post-COVID-19 syndrome.
dc.description.fulltextYES
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.issue17
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipN/A
dc.description.versionPublisher version
dc.description.volume12
dc.identifier.doi10.3390/app12178593
dc.identifier.eissn2076-3417
dc.identifier.embargoNO
dc.identifier.filenameinventorynoIR03974
dc.identifier.quartileN/A
dc.identifier.scopus2-s2.0-85137922301
dc.identifier.urihttps://hdl.handle.net/20.500.14288/3664
dc.identifier.wos850957900001
dc.keywordsFatigue
dc.keywordsCOVID-19
dc.keywordsRehabilitation
dc.keywordsTelerehabilitation
dc.keywordsPost-COVID-19
dc.keywordsLong COVID
dc.keywordsPost-COVID-19 syndrome
dc.keywordsExercise
dc.language.isoeng
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)
dc.relation.grantnoNA
dc.relation.ispartofApplied Sciences
dc.relation.urihttp://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/10840
dc.subjectChemistry
dc.subjectEngineering
dc.subjectMaterials science
dc.subjectApplied physics
dc.titleImpact of rehabilitation on fatigue in post-Covid-19 patients: a systematic review and meta-analysis
dc.typeReview
dspace.entity.typePublication
local.contributor.kuauthorTaşkıran, Özden Özyemişçi
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit2School of Medicine
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relation.isOrgUnitOfPublication.latestForDiscoveryd02929e1-2a70-44f0-ae17-7819f587bedd
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