Publication:
Acute kidney injury from SGLT2 inhibitors: Potential mechanisms

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SCHOOL OF MEDICINE
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Hahn, Kai
Ejaz, A. Ahsan
Lanaspa, Miguel A.
Johnson, Richard J.

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Abstract

SGLT2 inhibitors have shown great promise in the management of diabetes mellitus and the prevention of cardiovascular complications, but increasing evidence suggests that their use can be associated with an increased risk of acute kidney injury. Insights into the mechanisms involved might help to identify individuals who are at risk of renal injury.

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Nature Portfolio

Subject

Urology, Nephrology

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Nature Reviews Nephrology

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10.1038/nrneph.2016.159

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03 - Good Health and Well-being
Over the last 15 years, the number of childhood deaths has been cut in half. This proves that it is possible to win the fight against almost every disease. Still, we are spending an astonishing amount of money and resources on treating illnesses that are surprisingly easy to prevent. The new goal for worldwide Good Health promotes healthy lifestyles, preventive measures and modern, efficient healthcare for everyone.

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