Publication:
Effectiveness of tranexamic acid on bleeding in conization

dc.contributor.coauthorErgen, Evrim Bostancı
dc.contributor.coauthorAktaş, Özgür
dc.contributor.coauthorÖzdemir, Pelin
dc.contributor.coauthorKabaca, Canan
dc.contributor.coauthorDenizli, Ayşe Betül Albayrak
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorGiray, Burak
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2025-01-19T10:31:09Z
dc.date.issued2023
dc.description.abstractObjective: Bleeding is the most common complication of conization of cervix. Hemostatic sutures, intraoperative ferric subsulfate, or vasopressin can be used when intraoperative bleeding occurred, whereas oral tranexamic acid (TA) may be used for post-operative bleeding. In this study, we aimed to find out whether intraoperative cervical TA administration in patients undergoing conization caused changes in the amount of intraoperative bleeding and post-operative hemogram. Material and Methods: Patients who have undergone cervical conization between January 2019 and July 2019 in Zeynep Kamil Health Application and Research Center Gynecological Diseases and Birth Clinic were evaluated. One hundred and five patients were included to our study. One ampoule of 10% TA was applied cervically to 47 of these patients. Both groups were evaluated in terms of measuring the intraoperative amount of blood in the aspirator, changes in post-operative hb/htc/plt values compared to the pre-operative values, and the rate of post-operative bleeding. Results: In our study, the amount of intraoperative hemorrhage and pre-operative hemoglobin, hematocrit, and platelet values compared to the post-operative values were found to be similar in both groups. Conclusion: Although TA has been shown to be effective on hemorrhage in benign gynecologic operations, menorrhagia, and postpartum hemorrhages, no significant effect on hemorrhage in conization with cervical TA administration has been demonstrated.
dc.description.indexedbyTR Dizin
dc.description.issue4
dc.description.publisherscopeNational
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume26
dc.identifier.doi10.14744/zkmj.2022.62534
dc.identifier.eissn2757-8062
dc.identifier.quartileN/A
dc.identifier.urihttps://doi.org/10.14744/zkmj.2022.62534
dc.identifier.urihttps://hdl.handle.net/20.500.14288/26166
dc.keywordsCervical cytology
dc.keywordsCervical intraepithelial neoplasia
dc.keywordsConization
dc.keywordsHuman papilloma virus
dc.keywordsTranexamic acid
dc.language.isoeng
dc.publisherKare Publishing
dc.relation.ispartofZeynep Kamil Medical Journal
dc.subjectMedicine
dc.titleEffectiveness of tranexamic acid on bleeding in conization
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorGiray, Burak
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit2School of Medicine
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