Publication: Outcomes of transcatheter pulmonary SAPIEN 3 valve implantation: an international registry
dc.contributor.coauthor | Hascoet, Sebastien | |
dc.contributor.coauthor | Bentham, James R. | |
dc.contributor.coauthor | Giugno, Luca | |
dc.contributor.coauthor | Betrian-Blasco, Pedro | |
dc.contributor.coauthor | Kempny, Aleksander | |
dc.contributor.coauthor | Houeijeh, Ali | |
dc.contributor.coauthor | Baho, Haysam | |
dc.contributor.coauthor | Sharma, Shiv-Raj | |
dc.contributor.coauthor | Jones, Matthew, I | |
dc.contributor.coauthor | Biernacka, Elzbieta Katarzyna | |
dc.contributor.coauthor | Combes, Nicolas | |
dc.contributor.coauthor | Georgiev, Stanimir | |
dc.contributor.coauthor | Bouvaist, Helene | |
dc.contributor.coauthor | Martins, Jose Diogo | |
dc.contributor.coauthor | Kantzis, Marinos | |
dc.contributor.coauthor | Turner, Mark | |
dc.contributor.coauthor | Schubert, Stephan | |
dc.contributor.coauthor | Jalal, Zakaria | |
dc.contributor.coauthor | Butera, Gianfranco | |
dc.contributor.coauthor | Malekzadeh-Milani, Sophie | |
dc.contributor.coauthor | Valdeolmillos, Estibaliz | |
dc.contributor.coauthor | Karsenty, Clement | |
dc.contributor.coauthor | Odemis, Ender | |
dc.contributor.coauthor | Aldebert, Philippe | |
dc.contributor.coauthor | Haas, Nikolaus A. | |
dc.contributor.coauthor | Khatib, Ihab | |
dc.contributor.coauthor | Wahlander, Hakan | |
dc.contributor.coauthor | Gaio, Gianpiero | |
dc.contributor.coauthor | Mendoza, Alberto | |
dc.contributor.coauthor | Arif, Sayqa | |
dc.contributor.coauthor | Castaldi, Biagio | |
dc.contributor.coauthor | Dohlen, Gaute | |
dc.contributor.coauthor | Carere, Ronald G. | |
dc.contributor.coauthor | Del Cerro-Marin, Maria Jesus | |
dc.contributor.coauthor | Kitzmueller, Erwin | |
dc.contributor.coauthor | Hermuzi, Antony | |
dc.contributor.coauthor | Carminati, Mario | |
dc.contributor.coauthor | Guerin, Patrice | |
dc.contributor.coauthor | Tengler, Anja | |
dc.contributor.coauthor | Fraisse, Alain | |
dc.contributor.department | School of Medicine | |
dc.contributor.kuauthor | Ödemiş, Ender | |
dc.contributor.schoolcollegeinstitute | SCHOOL OF MEDICINE | |
dc.date.accessioned | 2025-01-19T10:33:11Z | |
dc.date.issued | 2023 | |
dc.description.abstract | Background and Aims Transcatheter pulmonary valve implantation (TPVI) is indicated to treat right-ventricular outflow tract (RVOT) dysfunction related to congenital heart disease (CHD). Outcomes of TPVI with the SAPIEN 3 valve that are insufficiently documented were investigated in the EUROPULMS3 registry of SAPIEN 3-TPVI.Methods Patient-related, procedural, and follow-up outcome data were retrospectively assessed in this observational cohort from 35 centres in 15 countries.Results Data for 840 consecutive patients treated in 2014-2021 at a median age of 29.2 (19.0-41.6) years were obtained. The most common diagnosis was conotruncal defect (70.5%), with a native or patched RVOT in 50.7% of all patients. Valve sizes were 20, 23, 26, and 29 mm in 0.4%, 25.5%, 32.1%, and 42.0% of patients, respectively. Valve implantation was successful in 98.5% [95% confidence interval (CI), 97.4%-99.2%] of patients. Median follow-up was 20.3 (7.1-38.4) months. Eight patients experienced infective endocarditis; 11 required pulmonary valve replacement, with a lower incidence for larger valves (P = .009), and four experienced pulmonary valve thrombosis, including one who died and three who recovered with anticoagulation. Cumulative incidences (95%CI) 1, 3, and 6 years after TPVI were as follows: infective endocarditis, 0.5% (0.0%-1.0%), 0.9% (0.2%-1.6%), and 3.8% (0.0%-8.4%); pulmonary valve replacement, 0.4% (0.0%-0.8%), 1.3% (0.2%-2.4%), and 8.0% (1.2%-14.8%); and pulmonary valve thrombosis, 0.4% (0.0%-0.9%), 0.7% (0.0%-1.3%), and 0.7% (0.0%-1.3%), respectively.Conclusions Outcomes of SAPIEN 3 TPVI were favourable in patients with CHD, half of whom had native or patched RVOTs. Structured Graphical Abstract Cumulative incidence of valvular replacement after transcatheter pulmonary SAPIEN 3 valve implantation in patients with congenital heart diseases 10.1093/eurheartj/ehad663_audio1 Audio Abstract ehad663_audio1 6339523571112 | |
dc.description.indexedby | WOS | |
dc.description.indexedby | Scopus | |
dc.description.indexedby | PubMed | |
dc.description.issue | 3 | |
dc.description.publisherscope | International | |
dc.description.sponsoredbyTubitakEu | N/A | |
dc.description.sponsorship | This work was supported by a research grant to the Department of Research and Innovation, Marie Lannelongue Hospital, Groupe Hospitalier Paris-Saint Joseph, France. | |
dc.description.volume | 45 | |
dc.identifier.doi | 10.1093/eurheartj/ehad663 | |
dc.identifier.eissn | 1522-9645 | |
dc.identifier.issn | 0195-668X | |
dc.identifier.quartile | Q1 | |
dc.identifier.scopus | 2-s2.0-85181891896 | |
dc.identifier.uri | https://doi.org/10.1093/eurheartj/ehad663 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14288/26563 | |
dc.identifier.wos | 1091004400001 | |
dc.keywords | Pulmonary valve | |
dc.keywords | Congenital heart disease | |
dc.keywords | Percutaneous pulmonary valve implantation | |
dc.keywords | Transcatheter pulmonary valve replacement | |
dc.keywords | SAPIEN 3 | |
dc.keywords | SAPIEN 3 Ultra | |
dc.language.iso | eng | |
dc.publisher | Oxford Univ Press | |
dc.relation.grantno | Department of Research and Innovation, Marie Lannelongue Hospital, Groupe Hospitalier Paris-Saint Joseph, France | |
dc.relation.ispartof | European Heart Journal | |
dc.subject | Medicine | |
dc.title | Outcomes of transcatheter pulmonary SAPIEN 3 valve implantation: an international registry | |
dc.type | Journal Article | |
dspace.entity.type | Publication | |
local.contributor.kuauthor | Ödemiş, Ender | |
local.publication.orgunit1 | SCHOOL OF MEDICINE | |
local.publication.orgunit2 | School of Medicine | |
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