Publication: Association between diabetes technology use and glycemic outcomes in adults with Type 1 Diabetes over a decade
dc.contributor.coauthor | Akturk, Halis K. | |
dc.contributor.coauthor | Alonso, G. Todd | |
dc.contributor.coauthor | Snell-Bergeon, Janet K. | |
dc.contributor.coauthor | Shah, Viral N. | |
dc.contributor.department | School of Medicine | |
dc.contributor.kuauthor | Karakuş, Kağan Ege | |
dc.contributor.schoolcollegeinstitute | SCHOOL OF MEDICINE | |
dc.date.accessioned | 2025-01-19T10:32:18Z | |
dc.date.issued | 2023 | |
dc.description.abstract | OBJECTIVE To evaluate change in mean clinic HbA1c from 2014 to 2021 with diabetes technology use in adults with type 1 diabetes. RESEARCH DESIGN AND METHODS In this single-center study, we analyzed diabetes technology use and mean clinic HbA1c among unique adults (age ‡18 years) with type 1 diabetes (last visit of the year per patient) between 1 January 2014 and 31 December 2021 from the electronic medical record. Diabetes technology use was defined as the use of continuous glucose monitors (CGMs) without an automated insulin delivery (AID) system or an AID system. Diabetes technology use and HbA1c over time were analyzed using mixedmodelsadjustedforage,sex,andvisityear. RESULTS A total of 15,903 clinic visits over 8 years (mean 1,988 patients per year, 4,174 unique patients, 52.7% female, 80.0% Non-Hispanic White) showed significant increases in CGM and AID use (P < 0.001 for both), resulting in an increase of diabetes technology use from 26.9% in 2014 to 82.7% in 2021. These increases were associated with a lower mean clinic HbA1c (7.7–7.5%, P < 0.001) and a higher percentage of adults achieving an HbA1c <7.0% (32.3–41.7%, P < 0.001) from 2014 to 2021. The HbA1c difference between technology users and nonusers increased over time from 0.36% (95% CI 0.26–0.47%, P < 0.001) in 2014 to 0.93% (95% CI 0.80–1.06%, P < 0.001) in 2021. CONCLUSIONS Adopting diabetes technology in adults with type 1 diabetes decreased HbA1c and increased the number of people achieving an HbA1c <7.0%, supporting the current international recommendation to offer AID systems to most individuals with type 1 diabetes. © 2023 by the American Diabetes Association. | |
dc.description.indexedby | WOS | |
dc.description.indexedby | Scopus | |
dc.description.indexedby | PubMed | |
dc.description.issue | 9 | |
dc.description.publisherscope | International | |
dc.description.sponsoredbyTubitakEu | N/A | |
dc.description.sponsorship | Duality of Interest. H.K.A. received, through the University of Colorado, research support from Dexcom, Medtronic, Tandem Diabetes, Eli Lilly, Senseonics, IM Therapeutics, REMD Biotherapeu-tics, and the International Association of Forensic Mental Health Services and honoraria from Man-nkind and Senseonics for advisory board attendance. V.N.S. reported receiving, through the University of Colorado, research support from Novo Nordisk, Insulet, Tandem Diabetes, and Dexcom and honoraria from Medscape, Lifescan, Novo Nordisk, and DKSH Singapore for advisory board attendance and from Insulet and Dexcom for speaking engagements. No other potential conflicts of interest relevant to this article were reported. Author Contributions. K.E.K., H.K.A., and V.N.S. were involved in the conception, design, and conduct of the study and wrote the first draft of the manuscript. G.T.A. and J.K.S.-B. were involved in the analysis and interpretation of the results. All authors edited, reviewed, and approved the final version of the manuscript. V.N.S. is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Prior Presentation. Parts of this study were presented at the 16th International Conference on Advanced Technologies and Treatments for Diabetes, Berlin, Germany, 22–25 February 2023. | |
dc.description.volume | 46 | |
dc.identifier.doi | 10.2337/dc23-0495 | |
dc.identifier.eissn | 1935-5548 | |
dc.identifier.issn | 1495992 | |
dc.identifier.quartile | Q1 | |
dc.identifier.scopus | 2-s2.0-85168796888 | |
dc.identifier.uri | https://doi.org/10.2337/dc23-0495 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14288/26366 | |
dc.identifier.wos | 1142330100011 | |
dc.keywords | Adolescent | |
dc.keywords | Adult | |
dc.keywords | Blood glucose | |
dc.keywords | Blood glucose self-monitoring | |
dc.keywords | Diabetes mellitus, Type 1 | |
dc.keywords | Glycated hemoglobin | |
dc.keywords | Hypoglycemic agents | |
dc.keywords | insulin | |
dc.keywords | Pancreas | |
dc.language.iso | eng | |
dc.publisher | American Diabetes Association Inc. | |
dc.relation.grantno | International Association of Forensic; University of Colorado, CU; Novo Nordisk | |
dc.relation.ispartof | Diabetes Care | |
dc.subject | Medicine | |
dc.title | Association between diabetes technology use and glycemic outcomes in adults with Type 1 Diabetes over a decade | |
dc.type | Journal Article | |
dspace.entity.type | Publication | |
local.contributor.kuauthor | Karakuş, Kağan Ege | |
local.publication.orgunit1 | SCHOOL OF MEDICINE | |
local.publication.orgunit2 | School of Medicine | |
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relation.isOrgUnitOfPublication.latestForDiscovery | d02929e1-2a70-44f0-ae17-7819f587bedd | |
relation.isParentOrgUnitOfPublication | 17f2dc8e-6e54-4fa8-b5e0-d6415123a93e | |
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