Publication: Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells
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KU Authors
Co-Authors
Onbasli, Kubra
Demirci, Gozde
Isik, Furkan
Durmusoglu, Emek Goksu
Demir, Hilmi Volkan
Acar, Havva Yagci
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N/A
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Abstract
Fluorescent, CdSe/CdS core/crown heterostructured nanoplatelets (NPLs) were transferred to the water via a simple, single-step ligand exchange using 2-mercaptopropionic acid in a simple extraction process. These stable, aqueous NPLs were loaded with a modal drug, 5-aminolevulinic acid (ALA). ALA-loaded NPLs emerged as a new class of theranostic nanoparticles for image-guided enhanced photodynamic therapy of both androgen-dependent and -independent human prostate cancer cells.
Source
Publisher
Royal Soc Chemistry
Keywords
Chemistry
Citation
Has Part
Source
Chemical Communications
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DOI
10.1039/d3cc02929h
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