Biosensors for prostate cancer detection

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dc.contributor.authorid0000-0003-4604-217X
dc.contributor.authoridN/A
dc.contributor.authorid0000-0002-5295-5701
dc.contributor.authorid0000-0002-5693-350X
dc.contributor.authorid0000-0003-2542-8110
dc.contributor.coauthorYetisen, Ali K.
dc.contributor.departmentDepartment of Mechanical Engineering
dc.contributor.departmentN/A
dc.contributor.departmentN/A
dc.contributor.departmentN/A
dc.contributor.departmentN/A
dc.contributor.kuauthorTaşoğlu, Savaş
dc.contributor.kuauthorSöylemez, Cansu
dc.contributor.kuauthorSarabi, Misagh Rezapour
dc.contributor.kuauthorNakhjavani, Sattar Akbar
dc.contributor.kuauthorTokyay, Begüm Kübra
dc.contributor.kuprofileFaculty Member
dc.contributor.kuprofilePhD Student
dc.contributor.kuprofilePhD Student
dc.contributor.kuprofileResearcher
dc.contributor.kuprofilePhD Student
dc.contributor.researchcenterKoç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM)
dc.contributor.researchcenterKU Arçelik Research Center for Creative Industries (KUAR) / KU Arçelik Yaratıcı Endüstriler Uygulama ve Araştırma Merkezi (KUAR)
dc.contributor.schoolcollegeinstituteCollege of Engineering
dc.contributor.schoolcollegeinstituteGraduate School of Sciences and Engineering
dc.contributor.schoolcollegeinstituteGraduate School of Sciences and Engineering
dc.contributor.schoolcollegeinstituteN/A
dc.contributor.schoolcollegeinstituteGraduate School of Sciences and Engineering
dc.contributor.yokid291971
dc.contributor.yokidN/A
dc.contributor.yokidN/A
dc.contributor.yokidN/A
dc.contributor.yokidN/A
dc.date.accessioned2025-01-19T10:33:08Z
dc.date.issued2023
dc.description.abstractProstate cancer (PC) is one of the most common tumors and a leading cause of mortality among men, resulting in similar to 375 000 deaths annually worldwide. Various analytical methods have been designed for quantitative and rapid detection of PC biomarkers. Electrochemical (EC), optical, and magnetic biosensors have been developed to detect tumor biomarkers in clinical and point-of-care (POC) settings. Although POC biosensors have shown potential for detection of PC biomarkers, some limitations, such as the sample preparation, should be considered. To tackle such shortcomings, new technologies have been utilized for development of more practical biosensors. Here, biosensing platforms for the detection of PC biomarkers such as immunosensors, aptasensors, genosensors, paper-based devices, microfluidic systems, and multiplex high-throughput platforms, are discussed.
dc.description.indexedbyWoS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue10
dc.description.openaccesshybrid
dc.description.publisherscopeInternational
dc.description.sponsorsS.T. acknowledges financial support from Tubitak 2232 International Fellowship for Outstanding Researchers Award (118C391) , Alexander von Humboldt Research Fellowship for Experienced Researchers, Marie Sk lodowska-Curie Individual Fellowship (101003361) , and Royal Academy Newton-Katip Celebi Transforming Systems Through Partnership award (120N019) . This work was partially supported by Science Academy 's Young Scientist Awards Program (BAGEP) , Outstanding Young Scientists Awards (GEB & Idot;P) , and Bilim Kahramanlari Dernegi The Young Scientist Award. Opinions, interpretations, conclusions, and recommendations are those of the authors and are not necessarily endorsed by the TUEB & Idot;TAK. This study was conducted using the service and infrastructure of Koc University Translational Medicine Research Center (KUTTAM) . The authors have no aff iliation or financial involvement with any organization or entity with a financial interest in or financial con flict with the subject matter or materials discussed in the manuscript apart from those disclosed.
dc.description.volume41
dc.identifier.doi10.1016/j.tibtech.2023.04.001
dc.identifier.eissn1879-3096
dc.identifier.issn0167-7799
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-85156117388
dc.identifier.urihttps://doi.org/10.1016/j.tibtech.2023.04.001
dc.identifier.urihttps://hdl.handle.net/20.500.14288/26553
dc.identifier.wos1082029300001
dc.keywordsBiomarkers
dc.keywordsBiosensors
dc.keywordsHealthcare
dc.keywordsPoint of care
dc.keywordsProstate cancer
dc.languageen
dc.publisherCell Press
dc.relation.grantnoTubitak 2232 International Fellowship for Outstanding Researchers Award [118C391]; Alexander von Humboldt Research Fellowship for Experienced Researchers, Marie Sklodowska-Curie Individual Fellowship [101003361]; Royal Academy Newton-Katip Celebi Transforming Systems Through Partnership award [120N019]; Science Academy 's Young Scientist Awards Program (BAGEP); Outstanding Young Scientists Awards (GEB Idot;P); Bilim Kahramanlari Dernegi The Young Scientist Award
dc.sourceTrends in Biotechnology
dc.subjectBiotechnology
dc.subjectMechanical engineering
dc.titleBiosensors for prostate cancer detection
dc.typeReview

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