Publication: Pancreatic steatosis is an independent risk factor for post-transplant diabetes mellitus in kidney transplant patients
dc.contributor.coauthor | Siriopol, Dimitrie (55135889900 | |
dc.contributor.department | School of Medicine | |
dc.contributor.kuauthor | Kanbay, Mehmet | |
dc.contributor.kuauthor | Hasbal, Nuri Barış | |
dc.contributor.kuauthor | Peltek, İbrahim Batuhan | |
dc.contributor.kuauthor | Atalay, Hande Özen | |
dc.contributor.kuauthor | Karakaya, Afak Durur | |
dc.contributor.kuauthor | Kesgin, Yavuz Erkam | |
dc.contributor.kuauthor | Mutlu, Ali | |
dc.contributor.kuauthor | Çöpür, Sidar | |
dc.contributor.kuauthor | Koçak, Burak | |
dc.contributor.schoolcollegeinstitute | SCHOOL OF MEDICINE | |
dc.date.accessioned | 2025-01-19T10:31:28Z | |
dc.date.issued | 2023 | |
dc.description.abstract | Background and Aim: Post-transplant diabetes mellitus (PTDM) is associated with an increased risk of post-transplant cardiovascular diseases, and several risk factors of PTDM have been shown in the literature. Yet, the relationship between hepatic and pancreatic steatosis with post-transplant diabetes mellitus remains vague. We aimed to evaluate pancreatic steatosis, a novel component of metabolic syndrome, and hepatic steatosis association with post-transplant diabetes mellitus in a single-center retrospective cohort study conducted on kidney transplant recipients.Method: We have performed a single-center retrospective cohort study involving all kidney transplant recipients. We have utilized pretransplant Fibrosis-4, nonalcoholic fatty liver disease fibrosis score, and abdominal computed tomography for the assessment of visceral steatosis status.Results: We have included 373 kidney transplant recipients with a mean follow-up period of 32 months in our final analysis. Post-transplant diabetes mellitus risk is associated with older age (p < .001), higher body-mass index (p < .001), nonalcoholic fatty liver disease-fibrosis score (p = .002), hepatic (p < .001) or pancreatic (p < .001) steatosis on imaging and higher pre-transplant serum triglyceride (p = .003) and glucose levels (p = .001) after multivariate analysis.Conclusion: Our study illustrates that recipients' pancreatic steatosis is an independent predictive factor for post-transplant diabetes mellitus including in kidney transplant patients. | |
dc.description.indexedby | WOS | |
dc.description.indexedby | Scopus | |
dc.description.indexedby | PubMed | |
dc.description.issue | 1 | |
dc.description.publisherscope | International | |
dc.description.sponsoredbyTubitakEu | N/A | |
dc.description.volume | 38 | |
dc.identifier.doi | 10.1111/ctr.15204 | |
dc.identifier.eissn | 1399-0012 | |
dc.identifier.issn | 0902-0063 | |
dc.identifier.quartile | Q2 | |
dc.identifier.scopus | 2-s2.0-85178395569 | |
dc.identifier.uri | https://doi.org/10.1111/ctr.15204 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14288/26251 | |
dc.identifier.wos | 1112537600001 | |
dc.keywords | Kidney transplantation | |
dc.keywords | Non-alcoholic fatty liver | |
dc.keywords | Pancreatic steatosis | |
dc.keywords | Post-transplant diabetes mellitus | |
dc.language.iso | eng | |
dc.publisher | Wiley | |
dc.relation.ispartof | Clinical Transplantation | |
dc.subject | Surgery | |
dc.subject | Transplantation | |
dc.subject | Medicine | |
dc.title | Pancreatic steatosis is an independent risk factor for post-transplant diabetes mellitus in kidney transplant patients | |
dc.type | Journal Article | |
dspace.entity.type | Publication | |
local.contributor.kuauthor | Hasbal, Nuri Barış | |
local.contributor.kuauthor | Kanbay, Mehmet | |
local.contributor.kuauthor | Çöpür, Sidar | |
local.contributor.kuauthor | Peltek, İbrahim Batuhan | |
local.contributor.kuauthor | Mutlu, Ali | |
local.contributor.kuauthor | Atalay, Hande Özen | |
local.contributor.kuauthor | Kesgin, Yavuz Erkam | |
local.contributor.kuauthor | Karakaya, Afak Durur | |
local.contributor.kuauthor | Koçak, Burak | |
local.publication.orgunit1 | SCHOOL OF MEDICINE | |
local.publication.orgunit2 | School of Medicine | |
relation.isOrgUnitOfPublication | d02929e1-2a70-44f0-ae17-7819f587bedd | |
relation.isOrgUnitOfPublication.latestForDiscovery | d02929e1-2a70-44f0-ae17-7819f587bedd | |
relation.isParentOrgUnitOfPublication | 17f2dc8e-6e54-4fa8-b5e0-d6415123a93e | |
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