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Permanent URI for this collectionhttps://hdl.handle.net/20.500.14288/6

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Now showing 1 - 7 of 7
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    PublicationOpen Access
    Response to "Clarification needed for case presented in 'the excision of the buccal fat pad for cheek refinement: volumetric considerations'"
    (Oxford University Press (OUP), 2019) N/A; N/A; Sezgin, Billur; Tatar, Sedat; Bƶge, Medine; Ɩzmen, Selahattin; Yavuzer, Cahit Reha; Faculty Member; Faculty Member; School of Medicine
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    PublicationOpen Access
    Gamma Knife radiosurgery for tuberculum sellae meningiomas: a series of 78 consecutive patients
    (Springer Nature, 2022) Peker, SelƧuk; Ardor, GƶkƧe Deniz; Samancı, Mustafa Yavuz; Faculty Member; Researcher; School of Medicine; KoƧ University Hospital; 11480; N/A; N/A
    Outcomes of Gamma Knife radiosurgery (GKRS) for tuberculum sellae meningiomas (TSMs) have not been reported explicitly within any meningioma series. We present the first and largest TSM series with clinical, radiosurgical, and outcome features for 78 consecutive patients managed with GKRS. Patients who underwent GKRS for TSMs between 2005 and 2021 and had a minimum of 6 months of follow-up were included. Medical records, imaging studies, and follow-up examinations were evaluated retrospectively. A total of 78 patients with a median age of 50.5 years were included. SRS was conducted as an upfront treatment for 38 patients (48.7%). The median target volume was 1.7 cm(3) (range, 0.1-14.6). During a median follow-up of 78.5 months, the cumulative PFS rates of the whole cohort at 1, 5, and 10 years by Kaplan-Meier analysis were 100%, 97.9%, and 94.5%, respectively. Of 47 patients with impaired vision, improvement and/or preservation of visual acuity, and visual field were achieved in 55.3% and 42.6%, respectively. No new-onset hormonal deficits were observed. Based on our data, SRS represents an effective and safe modality for unresected or recurrent/residual TSMs. SRS should be offered to patients who are not willing or not ideal candidates for surgery.
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    PublicationOpen Access
    Anatomical fundamentals and current surgical knowledge of prostate anatomy related to functional and oncological outcomes for robotic-assisted radical prostatectomy
    (Frontiers, 2022) Hoeh, Benedikt; Wenzel, Mike; Hohenhorst, Lukas; Koellermann, Jens; Graefen, Markus; Haese, Alexander; Walz, Jochen; Kosiba, Marina; Becker, Andreas; Banek, Severine; Kluth, Luis A.; Mandel, Philipp; Karakiewicz, Pierre I.; Chun, Felix K. H.; Preisser, Felix; Tilki, Derya; Other; School of Medicine; KoƧ University Hospital
    Context: meticulous knowledge about the anatomy of the prostate and surrounding tissue represents a crucial and mandatory requirement during radical prostatectomy for reliable oncological and excellent replicable, functional outcomes. Since its introduction two decades ago, robotic-assisted laparoscopic radical prostatectomy (RALP) has evolved to become the predominant surgical approach in many industrialized countries. Objective: to provide and highlight currently available literature regarding prostate anatomy and to help in improving oncological and functional outcomes in RALP. Methods/Evidence Acquiring: PubMed database was searched using the following keywords: ā€œrobotic-assisted radical prostatectomy,ā€ ā€œanatomy,ā€ ā€œneurovascular bundle,ā€ ā€œnerve,ā€ ā€œperiprostatic fascia,ā€ ā€œpelvis,ā€ ā€œsphincter,ā€ ā€œurethra,ā€ ā€œurinary incontinence,ā€ and ā€œerectile dysfunction.ā€ Relevant articles and book chapters were critically reviewed and if eligible, they were included in this review. Results: new evidence in regards to prostatic anatomy and surgical approaches in RALP has been reported in recent years. Besides detailed anatomical studies investigating the meticulous structure of the fascial structures surrounding the prostate and neurovascular bundle preservation, debate about the optimal RALP approach is still ongoing, inspired by recent publications presenting promising functional outcomes following modifications in surgical approaches. Conclusions: this review provides a detailed overview of the current knowledge of prostate anatomy, its surrounding tissue, and its influence on key surgical step development for RALP.
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    PublicationOpen Access
    Surgery for cystic pancreatic lesions in the post-Sendai era: a single institution experience
    (Hindawi, 2015) Kleeff, J.; Michalski, C.; Kong, B.; Roth, S.; Friess, H.; Siveke, J.; Esposito, I.; N/A; Erkan, Murat Mert; Faculty Member; School of Medicine; 214689
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    PublicationOpen Access
    Is elective cancer surgery feasible during the lock-down period of the COVID-19 pandemic? Analysis of a single institutional experience of 404 consecutive patients
    (Wiley, 2021) Cesur, Ezgi; Kırış, Talat; Giray, Burak; Kulle, Cemil Burak; Azamat, Ä°brahim Fethi; Ağcaoğlu, Orhan; Dilege, Ece; Erkan, Murat Mert; Balık, Emre; Bilge, Orhan; Buğra, Dursun; Vatansever, Doğan; Taşkıran, Ƈağatay; Erus, Suat; Yavuz, Ɩmer; Tanju, Serhan; Dilege, ÅžĆ¼krĆ¼; Tarım, Kayhan; Kiremit, Murat Can; KılıƧ, Mert; Canda, Abdullah Erdem; Kordan, Yakup; Akyoldaş, Gƶktuğ; Solaroğlu, Ä°hsan; Sasani, Mehdi; Gƶkler, Ozan; Ɯnsaler, Selin; Altuntaş, Muzaffer Ozan; Hafız, Ayşenur MeriƧ; Şimşek, Sezai Aykın; Deveci, Mehmet Ali; Korkmaz, Murat; Ƈakar, Nahit; ErgƶnĆ¼l, Ɩnder; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Teaching Faculty; Faculty Member; Researcher; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Teaching Faculty; Teaching Faculty; Teaching Faculty; Faculty Member; Faculty Member; Doctor; Faculty Member; Faculty Member; School of Medicine; KoƧ University Hospital; N/A; N/A; 175476; 218050; 214689; 18758; 176833; 1758; 193687; 134190; 175565; N/A; 214690; 122573; 327605; N/A; N/A; 116202; 157552; N/A; 102059; N/A; 311179; 167909; 169795; 53676; N/A; 206311; N/A; 198906; 110398
    Background: we aimed to assess the feasibility and short-term clinical outcomes of surgical procedures for cancer at an institution using a coronavirus disease 2019 (COVID-19)-free surgical pathway during the peak phase of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Materials and methods: this was a single-center study, including cancer patients from all surgical departments, who underwent elective surgical procedures during the first peak phase between March 10 and June 30, 2020. The primary outcomes were the rate of postoperative SARS-CoV-2 infection and 30-day pulmonary or non-pulmonary related morbidity and mortality associated with SARS-CoV-2 disease. Results: four hundred and four cancer patients fulfilling inclusion criteria were analyzed. The rate of patients who underwent open and minimally invasive procedures was 61.9% and 38.1%, respectively. Only one (0.2%) patient died during the study period due to postoperative SARS-CoV2 infection because of acute respiratory distress syndrome. The overall non-SARS-CoV2 related 30-day morbidity and mortality rates were 19.3% and 1.7%, respectively; whereas the overall SARS-CoV2 related 30-day morbidity and mortality rates were 0.2% and 0.2%, respectively. Conclusions: under strict institutional policies and measures to establish a COVID-19-free surgical pathway, elective and emergency cancer operations can be performed with acceptable perioperative and postoperative morbidity and mortality.
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    PublicationOpen Access
    The excision of the buccal fat pad for cheek refinement: volumetric considerations
    (Oxford University Press (OUP), 2019) N/A; Sezgin, Billur; Tatar, Sedat; Bƶge, Medine; Ɩzmen, Selahattin; Yavuzer, Cahit Reha; Faculty Member; Faculty Member; School of Medicine
    Background: although the excision of the buccal fat pad has become very popular for achieving a slimmer midface, not all patients are good candidates for this procedure. Unfortunately, studies that provide guidelines by emphasizing volumetric and technical details are limited. Objectives: the study compared preoperative and postoperative volumetric data to identify the amount of tissue that can safely be removed and important technical concepts involved in lower cheek contouring with buccal fat pad excision. Methods: patients complaining of cheek fullness were evaluated to determine if they were good candidates for the procedure. Eligible patients were screened with transbuccal ultrasound to determine tissue volumes and anatomical details. Intraoperative and postoperative, 6th-month volume measurements were undertaken and residual tissues and vascular pedicles reevaluated. Results: ultrasound imaging showed that the mean preoperative volume of the fat pads was 11.67 Ā± 1.44 mL, and the mean postoperative volume was 8.58 Ā± 1.07 mL. The mean volume of the excised tissues was 2.74 Ā± 0.69 mL. Postoperative buccal fat pad volume values correlated with the reported average in the literature for the same age group. Conclusions: Buccal fat pad removal is an effective technique for refining the facial silhouette that should be reserved for patients with increased buccal fat pad volume. Removal of only the excessive portion of the fat pad is important because this structure provides significant volume in the midface that can be difficult to restore once aging affects the surrounding soft and bony tissue.
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    PublicationOpen Access
    Outcomes of robotic-assisted versus open radical cystectomy in a large-scale, contemporary cohort of bladder cancer patients
    (Wiley, 2022) Hoeh, Benedikt; Flammia, Rocco S.; Hohenhorst, Lukas; Sorce, Gabriele; Chierigo, Francesco; Panunzio, Andrea; Tian, Zhe; Saad, Fred; Gallucci, Michele; Briganti, Alberto; Terrone, Carlo; Shariat, Shahrokh F.; Graefen, Markus; Antonelli, Alessandro; Kluth, Luis A.; Becker, Andreas; Chun, Felix K. H.; Karakiewicz, Pierre, I.; Tilki, Derya; Other; School of Medicine; KoƧ University Hospital
    Background and objectives: to test for differences in perioperative outcomes and total hospital costs (THC) in nonmetastatic bladder cancer patients undergoing open (ORC) versus robotic-assisted radical cystectomy (RARC). Methods: we relied on the National Inpatient Sample database (2016-2019). Statistics consisted of trend analyses, multivariable logistic, Poisson, and linear regression models. Results Of 5280 patients, 1876 (36%) versus 3200 (60%) underwent RARC versus ORC. RARC increased from 32% to 41% (estimated annual percentage change [EAPC]: + 8.6%; p = 0.02). Rates of transfusion (8% vs. 16%), intraoperative (2% vs. 3%), wound (6% vs. 10%), and pulmonary (6% vs. 10%) complications were lower in RARC patients (all p < 0.05). Moreover, median length of stay (LOS) was shorter in RARC (6 vs. 7days; p < 0.001). Conversely, median THC (31,486 vs. 27,162$; p < 0.001) were higher in RARC. Multivariable logistic regression-derived odds ratios addressing transfusion (0.49), intraoperative (0.53), wound (0.68), and pulmonary (0.71) complications favored RARC (all p < 0.01). In multivariable Poisson and linear regression models, RARC was associated with shorter LOS (Rate ratio:0.86; p < 0.001), yet higher THC (Coef.:5,859$; p < 0.001). RARC in-hospital mortality was lower (1% vs. 2%; p = 0.04). Conclusions: RARC complications, LOS, and mortality appear more favorable than ORC, but result in higher THC. The favorable RARC profile contributes to its increasing popularity throughout the United States.