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Permanent URI for this communityhttps://hdl.handle.net/20.500.14288/2

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Department: search.filters.department.Department of Electrical and Electronics EngineeringSubject: search.filters.subject.Bioinformatics

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Now showing 1 - 4 of 4
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    Molecular communication transmitter architectures for the internet of bio-nano things
    (Institute of Electrical and Electronics Engineers Inc., 2022) Department of Electrical and Electronics Engineering; N/A; Akan, Özgür Barış; Civaş, Meltem; Faculty Member; PhD Student; Department of Electrical and Electronics Engineering; College of Engineering; Graduate School of Sciences and Engineering; 6647; N/A
    In this study, we investigate the nanomaterial-based approach for developing practical molecular communication transmitters (MC-Txs) for the Internet of Bio-Nano Things (IoBNT) applications, which are expected to be unconventional in many aspects. In particular, we focus on the most pressing challenges for MC-Tx architectures, namely controlling information molecule release and molecule replenishment, together with other aspects, selective molecule release and molecule leakage mitigation. We discuss promising nanomaterials and also identify potential challenges and research directions.
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    Nanosensor networks for smart health care
    (Elsevier, 2020) Abbasi, Naveed A.; Department of Electrical and Electronics Engineering; N/A; N/A; Department of Electrical and Electronics Engineering; Akan, Özgür Barış; Khan, Tooba; Civaş, Meltem; Çetinkaya, Oktay; Faculty Member; PhD Student; PhD Student; Other; Department of Electrical and Electronics Engineering; College of Engineering; Graduate School of Sciences and Engineering; Graduate School of Sciences and Engineering; College of Engineering; 6647; N/A; N/A; N/A
    Advent of nanoscale sensors has paved the way for countless applications envisioned in the concept of a Smart City. In this chapter, we are focusing on one of the most fundamental requirements of the smart city, that is, smart health care. Great advancements in personal health care are expected with the emergence of nanosensing devices; however, single nanosensor is limited in its processing power and storage; thus we need to form network of nanosensors for any health-care application. In this chapter, we first elaborate the communication paradigms for nanosensor network. Moreover, we discuss various smart health-care applications such as smart drug delivery, body area network, implantable devices to treat injuries or malfunctions, and Internet of Nano Things. In the end, we highlight the implementation challenges for the nanosensor network for biomedical applications.
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    Narrow escape problem in synaptic molecular communications
    (Association for Computing Machinery, Inc, 2022) Koca, Çağlar; Department of Electrical and Electronics Engineering; N/A; Akan, Özgür Barış; Civaş, Meltem; Faculty Member; PhD Student; Department of Electrical and Electronics Engineering; College of Engineering; Graduate School of Sciences and Engineering; 6647; N/A
    The narrow escape problem (NEP) is a well-known problem with many applications in cellular biology. It is especially important to understand synaptic molecular communications. Active regions of synapses, also known as apposition zones, are connected to synaptic cleft through narrow slits, from which neurotransmitters can escape to or return from the cleft into the apposition zones. While neurotransmitters leakage into the cleft might be desired for the reuptake process, escaping neurotransmitters might trigger an undesired, i.e., false-positive or action potential in the post-synaptic terminal. Obtaining analytic solutions to NEPs is very challenging due to its geometry dependency. Slight alterations in either or both shape or the size of the hole and the outer volume may cause drastic changes in the solution. Thus, we need a simulation-based approach to solve NEPs. However, NEP also requires the size of the hole to be much smaller than the dimensions of the volume. Combined with the requirement for Brownian motion, where the step size is much smaller than the dimensions of the volume, simulations can be prohibitively long, even for modern computers. Therefore, in this work, we suggest a simulation algorithm that simultaneously satisfies the NEP and Brownian motion simulation requirements. Our simulation framework can be used to quantify the neurotransmitter leakage within synaptic clefts.
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    Toward interdisciplinary synergies in molecular communications: perspectives from synthetic biology, nanotechnology, communications engineering and philosophy of science
    (Multidisciplinary Digital Publishing Institute (MDPI), 2023) Egan, Malcolm; Barros, Michael Taynnan; Booth, Michael; Llopis-Lorente, Antoni; Magarini, Maurizio; Martins, Daniel P.; Schäfer, Maximilian; Stano, Pasquale; Department of Electrical and Electronics Engineering; Kuşcu, Murat; Faculty Member; Department of Electrical and Electronics Engineering; College of Engineering; 316349
    Within many chemical and biological systems, both synthetic and natural, communication via chemical messengers is widely viewed as a key feature. Often known as molecular communication, such communication has been a concern in the fields of synthetic biologists, nanotechnologists, communications engineers, and philosophers of science. However, interactions between these fields are currently limited. Nevertheless, the fact that the same basic phenomenon is studied by all of these fields raises the question of whether there are unexploited interdisciplinary synergies. In this paper, we summarize the perspectives of each field on molecular communications, highlight potential synergies, discuss ongoing challenges to exploit these synergies, and present future perspectives for interdisciplinary efforts in this area.