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Publication Metadata only Challenges and practices arising during public health emergencies: a qualitative survey on ethics committees(John Wiley and Sons Inc, 2022) Ekmekci, Perihan Elif; Güner, Müberra Devrim; Buruk, Banu; Güneş, Begüm; Arda, Berna; Görkey, Şefik; Faculty Member; School of Medicine; 184451The particular dynamics of public health emergencies urge scientists and Ethics Committee (EC) members to change and adapt their operating procedures to function effectively. Despite having previous pandemic experiences, ethics committees were unprepared to adapt to COVID-19 pandemic challenges. This survey aims to learn and thoroughly discuss the most salient issues for ECs during the COVID-19 pandemic. The results indicate that the main problems faced by ECs were lack of/insufficient regulations, lack of data/experience/knowledge, sloppy review, poor research design, and poor adaptation to quarantine measures. Coping with factors that threaten the autonomy and independence of ECs, the ethical dilemma regarding maximizing common good versus protecting the rights and well-being of study participants, comprehending the change in the context of vulnerable populations, and redefining the role of ECs to strengthen trust in science and vaccine confidence were outstanding issues. © 2022 John Wiley & Sons Ltd.Publication Open Access COVID-19 and the global impact on colorectal practice and surgery(Elsevier, 2020) Nunoo-Mensah, Joseph W.; Rizk, Mariam; Caushaj, Philip F.; Giordano, Pasquale; Fortunato, Richard; Dulskas, Audrius; da Costa, Pereira Joaquim M.; Escalante, Ricardo; Koda, Keiji; Samalavicius, Narimantas E.; Maeda, Kotaro; Chun, Ho-Kyung; ISUCRS COVID-19 Participating Investigator Group; Buğra, Dursun; Faculty Member; School of MedicineBackground: the novel severe acute respiratory syndrome coronavirus 2 virus that emerged in December 2019 causing coronavirus disease 2019 (COVID-19) has led to the sudden national reorganization of health care systems and changes in the delivery of health care globally. The purpose of our study was to use a survey to assess the global effects of COVID-19 on colorectal practice and surgery. Materials and methods: a panel of International Society of University Colon and Rectal Surgeons (ISUCRS) selected 22 questions, which were included in the questionnaire. The questionnaire was distributed electronically to ISUCRS fellows and other surgeons included in the ISUCRS database and was advertised on social media sites. The questionnaire remained open from April 16 to 28, 2020. Results: a total of 287 surgeons completed the survey. Of the 287 respondents, 90% were colorectal specialists or general surgeons with an interest in colorectal disease. COVID-19 had affected the practice of 96% of the surgeons, and 52% were now using telemedicine. Also, 66% reported that elective colorectal cancer surgery could proceed but with perioperative precautions. Of the 287 respondents, 19.5% reported that the use of personal protective equipment was the most important perioperative precaution. However, personal protective equipment was only provided by 9.1% of hospitals. In addition, 64% of surgeons were offering minimally invasive surgery. However, 44% reported that enough information was not available regarding the safety of the loss of intra-abdominal carbon dioxide gas during the COVID-19 pandemic. Finally, 61% of the surgeons were prepared to defer elective colorectal cancer surgery, with 29% willing to defer for ≤ 8 weeks. Conclusion: the results from our survey have demonstrated that, globally, COVID-19 has affected the ability of colorectal surgeons to offer care to their patients. We have also discussed suggestions for various practical adaptation strategies for use during the recovery period. We have presented the results of a survey used to assess the global impact of coronavirus disease 2019 (COVID-19) on the delivery of colorectal surgery. Despite accessible guidance information, our results have demonstrated that COVID-19 has significantly affected the ability of colorectal surgeons to offer care to patients. We have also discussed practical adaptation strategies for use during the recovery phase.Publication Restricted COVID-19 salgını sırasında üniversite öğrencilerinin gösterdikleri tutumun COVID-19 korku düzeyleri üzerine olan etkisi(Koç University, 2021) Gündoğan, Serra; Beşer, Ayşe; 0000-0003-4039-7439; Koç University Graduate School of Health Sciences; Nursing; 143490Publication Restricted Developing a novel recombinant IL-1 receptor antagonist to treat the cytokine storm in COVID-19(Koç University, 2022) Beyaz, Burcu; Kızılel, Seda; 0000-0001-9092-2698; Koç University Graduate School of Sciences and Engineering; Bio-Medical Sciences and Engineering; 28376Publication Metadata only Education of healthcare personnel working with pediatric patients during covid-19 pandemic within the framework of infection control(AVES, 2020) Oygar P.D.; Büyükçam A.; Bal Z.Ş.; Dalgıç N.; Bozdemir Ş.E.; Karbuz A.; Çetin B.Ş.; Kara Y.; Çetin C.; Hatipoğlu N.; Uygun H.; Aygün F.D.; Törün S.H.; Okur D.Ş.; Çiftdoğan D.Y.; Kara T.T.; Yahşi A.; Özer A.; Demir S.Ö.; Akkoç G.; Turan C.; Salı E.; Şen S.; Erdeniz E.H.; Kara S.S.; Emiroğlu M.; Erat T.; Gürlevik S.L.; Sütçü M.; Aydın Z.G.G.; Atikan B.Y.; Yeşil E.; Güner G.; Çelebi E.; Efe K.; İşançlı D.K.; Durmuş H.S.; Tekeli S.; Karaarslan A.; Bülbül L.; Almış H.; Kaba Ö.; Keleş Y.E.; Yazıcıoğlu B.; Oğuz Ş.B.; Ovalı H.F.; Doğan H.H.; Çelebi S.; Çakır D.; Karasulu B.; Alkan G.; Gül D.; Küçükalioğlu B.P.; Avcu G.; Kukul M.G.; Bilen M.; Yaşar B.; Üstün T.; Kılıç Ö.; Akın Y.; Cebeci S.O.; Turgut M.; Yanartaş M.S.; Şahin A.; Arslanoğlu S.; Elevli M.; Öz Ş.K.T.; Hatipoğlu H.; Erkum İ.T.; Demirbuğa A.; Özçelik T.; Sarı E.E.; Akkuş G.; Hatipoğlu S.S.; Dinleyici E.Ç.; Hacımustafaoğlu M.; Özkınay F.; Kurugöl Z.; Cengiz A.B.; Somer A.; Tezer H.; Kara A.; N/A; Aktürk, Hacer; Yenidoğan, İrem; Faculty Member; Researcher; School of Medicine; School of Medicine; 162936; 327591Objective: In the early stages of any epidemic caused by new emerging pathogens healthcare personnel is subject to a great risk. Pandemic caused by SARS-CoV-2, proved to be no exception. Many healthcare workers died in the early stages of pandemic due to inadequate precautions and insufficient protection. It is essential to protect and maintain the safety of healthcare personnel for the confinement of pandemic as well as continuity of qualified healthcare services which is already under strain. Educating healthcare personnel on appropiate use of personal protective equipment (PPE) is as essential as procuring them. Material and Methods: A survey is conducted on 4927 healthcare personnel working solely with pediatric patients from 32 different centers. Education given on PPE usage were questioned and analyzed depending on age, sex, occupation and region. Results: Among four thousand nine hundred twelve healthcare personnel from 32 different centers 91% (n= 4457) received education on PPE usage. Of those who received education only 36% was given both theoretical and applied education. Although there was no differences among different occupation groups, receiving education depended on regions. Conclusion: It is essential to educate healthcare personnel appropiately nationwidely for the continuity of qualified healthcare services during the pandemic. © 2020, AVES. All rights reserved./ Öz: Giriş: Yeni ortaya çıkan patojenlerin neden olduğu salgınların erken dönemleri sağlık çalışanları için büyük bir risk taşımaktadır. SARS-CoV-2’nin neden olduğu pandemide de durum farklı olmamış, alınan yetersiz önlemler ve kişisel korunma eksikliği nedenleriyle pandemi başlangıcında birçok sağlık çalışanı hayatını kaybetmiştir. Sağlık çalışanlarının koruması ve güvenli ortamda çalışmalarının devamlılığının sağlanması sağlık hizmetlerinin aksamamasının yanında salgının sınırlandırması içinde gereklidir. Kişisel koruyucu ekipmaların kullanımı ile ilgili eğitimlerin verilmesi, gerekli durumlarda güncellenmesi koruyucu ekipmanların sağlanması kadar önemlidir. Gereç ve Yöntemler: Otuz iki farklı merkezde çocuklara sağlık hizmeti veren 4927 sağlık personeli üzerinde anket uygulanmış, kişisel koruyucu ekipman kullanımı konusunda alınan eğitim değerlendirilmiş, yaş, cinsiyet, meslek ve bölgesel farklılıkların eğitim alma üzerine etki edip etmediği değerlendirilmiştir. Bulgular: Otuz iki farklı merkezden 4927 sağlık çalışanın katıldığı çalışmada, 4457 (%91) sağlık çalışanın kişisel koruyucu ekipmaların kullanımı ile ilgili eğitim aldığı saptanmış, yalnızca %36’sının hem teorik hem de uygulamalı eğitim aldığı bulunmuştur. Meslek grupları arasında eğitim alma yönünden fark görülmezken, bölgelere göre eğitim alıp almamada anlamlı fark olduğu saptanmıştır. Sonuç: Tüm bölgelerde sağlık personelinin kişisel korunma konusunda eğitilmesi ve verilen eğitimin denetimi ve sürekliliği kaliteli sağlık hizmetlerinin devamlılığı için gereklidir.Publication Open Access Influence of the life style parameters including dietary habit, chronic stress and environmental factors and jobs on the human health in relation to COVID-19 pandemic(Cambridge University Press (CUP), 2020) Aydemir, Duygu; Ulusu, Nuriye Nuray; PhD Student; Faculty Member; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); School of Medicine; N/A; 6807Publication Restricted Investigation of host proteome changes in plasma of COVID-19 patients(Koç University, 2022) Yurtseven, Ali; Sıcakkan, Nurhan Özlü; 0000-0002-5157-8780; Koç University Graduate School of Sciences and Engineering; Molecular Biology and Genetics; 105301Publication Open Access Management of female and functional urology patients during the COVID pandemic(Elsevier, 2020) López-Fando, L.; Bueno, P.; Carracedo, D.; Averbeck, M.; Castro-Díaz, D.M.; Chartier-Kastler, E.; Cruz, F.; Dmochowski, R.; Finazzi-Agrò, E.; Hajebrahimi, S.; Heesakkers, J.; Kasyan, G.; Peyronnet, B.; Plata, M.; Padilla-Fernández, B.; Van Der Aa, F.; Arlandis, S.; Hashim, H.; Tarcan, Tufan; Other; School of Medicine; 173289Context: coronavirus disease 19 (COVID-19) has changed standard urology practice around the world. The situation is affecting not only uro-oncological patients but also patients with benign and disabling conditions who are suffering delays in medical attention that impact their quality of life. Objective: to propose, based on expert advice and current evidence where available, a strategy to reorganize female and functional urological (FFU) activity (diagnosis and treatment). Evidence acquisition: the present document is based on a narrative review of the limited data available in the urological literature on SARS-Cov-2 and the experience of FFU experts from several countries around the world. Evidence synthesis: in all the treatment schemes proposed in the literature on the COVID-19 pandemic, FFU surgery is not adequately covered and usually grouped into the category that is not urgent or can be delayed, but in a sustained pandemic scenario there are cases that cannot be delayed that should be considered for surgery as a priority. The aim of this document is to provide a detailed management plan for noninvasive and invasive FFU consultations, investigations, and operations. A classification of FFU surgical activity by indication and urgency is proposed, as well as recommendations adopted from the literature for good surgical practice and by surgical approach in FFU in the COVID-19 era. Conclusions: functional, benign, and pelvic floor conditions have often been considered suitable for delay in challenging times. The long-term implications of this reduction in functional urology clinical activity are currently unknown. This document will help functional urology departments to reorganize their activity to best serve their patients. Patient summary: many patients will suffer delays in urology treatment because of COVID-19, with consequent impairment of their physical and psychological health and deterioration of their quality of life. Efforts should be made to minimize the burden for this patient group, without endangering patients and health care workers. COVID-19 disease has changed standard urology practice worldwide. Most efforts have focused on urologic oncology. An international panel composed of opinion leaders in 13 countries proposes comprehensive guidelines on how to manage female and functional urology patients.Publication Open Access Oligosymptomatic kidney transplant patients with COVID-19: do they pose a risk to other recipients?(Elsevier, 2020) Arpalı, Emre; Akyollu, Başak; Koçak, Burak; Yelken, Berna; Kalayoğlu, Münci; Türkmen, Aydın; Tekin, Süda; Kanbay, Mehmet; Faculty Member; Doctor; Faculty Member; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; N/A; N/A; 110580The clinical course of viral infections in patients under immunosuppression can be atypical and/or fatal if not diagnosed and treated appropriately. The coronavirus disease 2019 (COVID-19) may also have an atypical presentation. Contrary to the general opinion, transplant patients may be asymptomatic or oligosymptomatic, which could be a risk factor for underdiagnosis and the dissemination of this viral disease. This study presents the clinical features of 2 oligosymptomatic kidney transplant patients diagnosed with COVID-19. We suggest that new screening algorithms for COVID-19 should be reconsidered for the transplant patient population.Publication Restricted The Impact of COVID-19 on the Willingness to Work in Teams(Koç University, 2021) Divle, Sündüz; Ertaç, Seda; 0000-0002-5077-5555; Koç University Graduate School of Social Sciences and Humanities; Economics; 107102