Researcher:
Ödemiş, Ender

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Ender

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Ödemiş

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Ödemiş, Ender

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2022 - 20237

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Researcher Of Publications: search.filters.isAuthorOfPublication.302421b6-1961-4d33-82f4-4532e32835c9

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Now showing 1 - 9 of 9
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    Does a prenatal diagnosis affect mortality and morbidity for neonatal arterial switch operation
    (Cambridge Univ Press, 2022) Guvenc, Osman; Beken, Serdar; Inamlik, Aysegul; Albayrak, Eda; Temur, Bahar; Basgoze, Serdar; Aydin, Selim; Saygi, Murat; Erek, Ersin; Toygar, Ayse Korkmaz; N/A; Ödemiş, Ender; Faculty Member; School of Medicine; 194545
    Background: The effect of prenatal diagnosis on prognosis in patients with transposition of the great arteries is not clear. In this study, we compared the outcomes after arterial switch operation. Methods: Outcome of 112 patients who had arterial switch operation in the neonatal period were analysed. The patients were divided into two groups: those who had prenatal diagnosis (Group 1; n = 34) and those who did not (Group 2; n = 78). The patients were also classified based on their diagnosis: simple transposition, transposition with ventricular septal defect and/or aortic arch hypoplasia, and Taussig-Bing anomaly. Results: In Group 1, the C-section delivery rate was higher (82% vs. 44%; p = 0.004), and it was observed that patients in Group 1 were more often intubated upon admission to the neonatal ICU (38% vs. 9%; p = 0.005). No differences were found between the two groups in terms of operation time, cardiopulmonary bypass time, post-operative invasive respiratory support duration, or extracorporeal membrane oxygenation support. It was observed that those who had Taussig-Bing anomaly had a higher mortality. Conclusions: Timely treatment have a positive effect on neonatal mortality and morbidity. That's why all families with prenatal diagnosis of critical CHD should be recommended to have the delivery in a tertiary care hospital. Although it could not be demonstrated in this study, prenatal diagnosis has a potential to improve surgical results especially in countries or cities, which does not have enough resources for transfer and surgical units. Further efforts are needed to improve prenatal screening programmes.
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    A rare complication after an interventional procedure using the common carotid: carotid pseudoaneurysm in an infant
    (Cambridge University Press (CUP), 2023) N/A; Biçer, Mehmet; Kızılkaya, Mete Han; Ödemiş, Ender; Gündoğmuş, Cemal Aydin; Faculty Member; Doctor; Faculty Member; Doctor; School of Medicine; N/A; School of Medicine; N/A; Koç University Hospital; 310599; N/A; 194545; N/A
    The carotid artery is a valuable vascular access that can be used in patients who have undergone repetitive interventional and surgical procedures and premature babies. In the past, cut-down was used but nowadays, mostly the procedure is performed under ultrasonographic guidance. Complications such as bleeding, haematoma, and pseudoaneurysm may occur when the carotid artery is used as a vascular access for the procedures such as aortic balloon valvuloplasty, coarctation balloon angioplasty, or after interventional or surgical treatments to the carotid artery. Although pseudoaneurysm is very rare, prompt diagnosis and accurate treatment planning are life-saving. In this article, the diagnosis and treatment of pseudoaneurysm in the left common carotid after transcatheter coarctation balloon angioplasty in a 6-month-old infant will be presented.
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    Early postnatal metabolic profile in neonates with critical CHDs
    (Cambridge University Press (CUP)) Guvenc, Osman; Beken, Serdar; Abali, Saygin; Saral, Neslihan Yildirim; Yalçın, Gizem; Albayrak, Eda; Bulum, Burcu; Demirelce, Ozlem; Basgoze, Serdar; Erek, Ersin; Serteser, Mustafa; Toygar, Ayse Korkmaz; N/A; Ödemiş, Ender; Faculty Member; School of Medicine; Koç University Hospital; 194545
    Background: Cyanotic CHD is a life-threatening condition that presents with low oxygen saturation in the newborn period. Hypoxemia might cause alterations in the metabolic pathways. In the present study, we aimed to evaluate the early postnatal amino acid and carnitine/acylcarnitine profiles of newborn infants with cyanotic CHD. Methods: A single centre case-control study was conducted. Twenty-seven patients with cyanotic CHD and 54 healthy newborn controls were enrolled. As part of the neonatal screening programme, results of amino acid and carnitine/acylcarnitine were recorded and compared between groups. Results: Twenty-seven neonates with cyanotic CHD and 54 healthy newborns as controls were enrolled in the study. Cyanotic CHD neonates had higher levels of alanine, phenylalanine, leucine/isoleucine, citrulline, ornithine, C5, C5-OH; but lower levels of C3, C10, C12, C14, C14:1, C16, C16.1, C18, C5-DC, C6-DC, C16-OH, C16:1-OH when compared with the healthy controls. Conclusion: This study showed that there are differences between patients with cyanotic CHD and healthy controls in terms of postnatal amino acid and carnitine/acylcarnitine profiles.
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    Early and mid-term outcomes of transcatheter closure of perimembranous ventricular septal defects using the lifetech (tm) konar-mf occluder device (mfo)
    (Cambridge Univ Press) N/A; N/A; Ödemiş, Ender; Kızılkaya, Mete Han; Faculty Member; Doctor; School of Medicine; N/A; N/A; Koç University Hospital; 194545; N/A
    Background: Transcatheter closure of perimembranous ventricular septal defects is challenging. Double disk-designed devices have high adverse event rates; therefore, research into new devices persists. One such devise is the LifetechTM Konar-MF Occluder device (MFO), which is increasingly used. The purpose of this study is to present mid-term results of MFO for transcatheter closure of patients with perimembraneous ventricular septal defect. Patients and methods: Records of the 52 patients with perimembraneous ventricular septal defect who had undergone transcatheter closure with MFO were reviewed. Demographic, echocardiographic, and procedure details were investigated. Three years follow-up results were recorded. Results: We closed the perimembraneous ventricular septal defect in 51 of 52 patients (98%). The femoral venous approach was used in 27 patients (53 %) whilst no arteriovenous loop was established in the remaining patients. No significant procedure-related complication occurred. On day 1 echocardiography, the residual ventricular septal defect rate was 31%. Mean +/- SD (range) follow-up duration was 36 +/- 7,9 (18-54) months. At 6th month follow-up, only four patients had haemodynamically significant residual defects. No severe dysrhythmia was detected including complete heart block. A right bundle branch block pattern was seen in one patient. Conclusion: This study showed that MFO is a safe and effective device in the transcatheter treatment of perimembraneous ventricular septal defect's with mid-term follow-up.
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    Early results of pulsta (R) transcatheter heart valve in patients with enlarged right ventricular outflow tract and severe pulmonary regurgitation due to transannular patch
    (Cambridge Univ Press, 2022) N/A; N/A; Ödemiş, Ender; Yenidoğan, İrem; Kızılkaya, Mete Han; Faculty Member; Researcher; Doctor; School of Medicine; School of Medicine; N/A; N/A; N/A; Koç University Hospital; 194545; 327591; N/A
    Objective: the purpose of this study is to assess the feasibility, effectivity, and safety of a novel self-expandable valve system, Pulsta (R) transcatheter heart valve in patients with tetralogy of fallot and severe pulmonary regurgitation after transannular patch repair. Background: Severe pulmonary regurgitation after tetralogy of fallot repair is a life-threatening problem and should be treated by pulmonary valve implantation. although percutaneous pulmonary valve implantation has been ever increasingly used for this purpose, Available balloon-expandable valves have limitations and cannot be used by most patients. Pulsta (R) transcatheter heart valve is a new self-expandable valve system and offers a new solution to be used in patients with different types of native right ventricular outflow tract geometry. Patients and Methods: Ten patients with severe regurgitation after tetralogy of fallot repair with a transannular patch have been enrolled in the study according to echocardiographic examination. MRI was used in asymptomatic patients to delineate the indication and the right ventricular outflow tract geometry. Pulsta (R) transcatheter heart valve implantation was performed in ten patients, and preprocedural, procedure, and 6 months follow-up findings of the patients were evaluated. Results: Pulsta (R) pulmonary valve implantation was performed in ten patients successfully without any severe complications. Valve functions were perfect in six of ten patients, while the others had insignificant regurgitation by echocardiographic examination at the end of 6 months follow-up. Conclusions: This study showed that Pulsta (R) transcatheter heart valve is a feasible, effective, and safe method in the treatment of severe pulmonary regurgitation due to transannular patch repair in patients with tetralogy of fallot.
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    Treatment of 12-year-old girl with midaortic syndrome by using Cook Formula stent
    (Cambridge Univ Press, 2022) N/A; N/A; Ödemiş, Ender; Çelikyurt, Aydın; Faculty Member; Researcher; School of Medicine; School of Medicine; 194545; 327610
    Middle aortic syndrome is a severe form of aortic coarctation and mostly involves the thoracic and abdominal part of the aorta. Traditional surgical approach has some potential risks and repetitive operations. Percutaneous stent implantation is a feasible and safe method for the palliation of middle aortic syndrome in childhood. Herein, a child with middle aortic syndrome was presented who has been treated by transcatheter stent implantation.
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    First experiences with myval transcatheter heart valve system in the treatment of severe pulmonary regurgitation in native right ventricular outflow tract and conduit dysfunction
    (Cambridge Univ Press, 2022) N/A; N/A; Ödemiş, Ender; Yenidoğan, İrem; Faculty Member; Researcher; School of Medicine; School of Medicine; 194545; 327591
    The rate of morbidity and mortality related to pulmonary regurgitation and pulmonary stenosis are big concerns after the surgery for CHD. Percutaneous pulmonary valve implantation has been established as a less invasive technique compared to surgery with promising results according to long-term follow-up of the patients. There are only two approved valve options for percutaneous pulmonary valve implantation until now, which are Melody (Medtronic, Minneapolis, Minn, USA) and Sapien (Edwards Lifesciences, Irvine, Ca, USA). Both valves have limitations and do not cover entire patient population. Therefore, the cardiologists need more options to improve outcomes with fewer complications in a such promising area. Herein, we present a case series applying for pulmonary position in conduits and native right ventricular outflow tract of a new transcatheter valve system Myval (R) which is designed for transcatheter aortic valve implantation procedures. This is the first patient series in which the use of Myvalv in dysfunctional right ventricular outflow tracts is described, after surgical repair of CHD.
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    Transcatheter management of life-threatening pulmonary arteriovenous fistula with extracorporeal membrane oxygenation support in an infant
    (Cambridge Univ Press, 2022) Güvenç, Osman; Saygı, Murat; Önalan, Mehmet Akif; N/A; Ödemiş, Ender; Faculty Member; School of Medicine; 194545
    Pulmonary arteriovenous malformation is a rare disease leading to cyanosis, where there is a direct relation between the pulmonary artery and pulmonary vein without a capillary structure. Arteriovenous fistulae may be single or multiple. Clinical signs emerge depending on the size of the fistulae and amount of shunt. Due to the advancements in transcatheter devices and increased experience render enable the fistula embolisation procedure as an alternative to surgical treatment. Extracorporeal membrane oxygenation is used to support the patient haemodynamically and respirationally in cases of treatment-resistant, severe and revocable cardiac or pulmonary sufficiency. This paper presents an infant patient with pulmonary arteriovenous malformation, who had haemodynamic instability due to severe hypoxia and received successful transcatheter fistula embolisation via extracorporeal membrane oxygenation under emergency conditions.
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    PublicationOpen Access
    Sequential percutaneous tricuspid and pulmonary valve implantation in a young child operated previously for Ebstein Anomaly
    (Cambridge University Press (CUP), 2022) Aydın, Selim; N/A; Ödemiş, Ender; Yenidoğan, İrem; Faculty Member; Researcher; Graduate School of Sciences and Engineering; Graduate School of Health Sciences
    We report a successful percutaneous tricuspid valve implantation followed by a percutaneous pulmonary valve implantation in a young child with Ebstein's anomaly of tricuspid valve and pulmonary stenosis who was previously treated surgically at 1 year of age with tricuspid ring annuloplasty and a transannular outflow patch. This article shows the feasibility of sequential implantation of two valves in young patients with severe tricuspid and pulmonary valve insufficiency.