Researcher:
Yiğit, Yeşim Esen

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Undergraduate Student

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Yeşim Esen

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Yiğit

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Yiğit, Yeşim Esen

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20202

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    PublicationOpen Access
    Far from luck's way: a concurrence of Kaposi sarcoma and cutaneous angiosarcoma in the setting of chronic lymphocytic leukemia
    (Medknow Publications, 2020) Sezgin, Billur; Yiğit, Yeşim Esen; Tatar, Sedat; Selçukbiricik, Fatih; Durankuş, Nilüfer Kılıç; Kulaç, İbrahim; Atasoy, Pınar; Faculty Member; Faculty Member; Faculty Member; School of Medicine; Koç University Hospital; 133762; N/A; N/A; 202015; N/A; 170305; N/A
    Kaposi sarcoma and cutaneous angiosarcoma are rare forms of skin malignancies that are vascular in nature and are frequently encountered in the immunosuppressed population. Although synchronous angiosarcoma and Kaposi sarcoma have been documented, to our knowledge, the coexistence of these vascular malignancies with underlying chronic lymphocytic leukemia has not been previously reported. A 51-year-old male patient with chronic lymphocytic leukemia presented with Kaposi sarcoma located on his left ankle. Shortly after, the patient presented with de novo lesions located on the plantar region of the right foot, reported as angiosarcoma. Following a multidisciplinary decision, treatment with adjuvant chemotherapy consisting of paclitaxel and carboplatin with consolidation radiotherapy was planned. The patient's Kaposi sarcoma has remained unchanged throughout this period.In such cases, the treatment is advised to be planned around the more aggressive malignancy. These patients should also be followed-up by dermatology due to the higher risk of secondary cutaneous malignancies.
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    PublicationOpen Access
    Upper socioeconomic status is associated with lower Helicobacter pylori infection rate among patients undergoing gastroscopy
    (The Journal of Infection in Developing Countries, 2020) Mungan, Zeynel; Attila, Tan; Zeybel, Müjdat; Yiğit, Yeşim Esen; Baran, Bülent; Ahıshalı, Emel; Alper, Emrah; Aslan, Fatih; Ergönül, Önder; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; School of Medicine; 118342; 214694; N/A; 167583; N/A; N/A; 219202; 110398
    Introduction: socioeconomic factors play an important role in the prevalence of Helicobacter pylori (HP) infection. The aim of this study is to investigate HP prevalence among symptomatic patients in the upper socioeconomic segment of the population undergoing gastroscopy in an endemic urban region. Methodology: over a 12-month period, data were collected from the first consecutive 1000 patients (500 from university hospital, 500 from community hospital) who had gastroscopy and HP evaluation. Results: overall, 211/1000 patients (21.1 %) were found to have HP in gastric biopsies. The specificity, sensitivity, positive predictive value, negative predictive value and diagnostic accuracy of rapid urease test were 87.5%, 99.7%, 99%, 96.5%, and 96.9% respectively. Atrophic gastritis, gastric and duodenal ulcers were significantly more common in HP positive patients. Age based distribution of HP prevalence: > 6 decades (15.5%), 3rd-5th decades (26.1%), < 3rd decades (10.4%). Conclusion: in an HP endemic country, the prevalence of HP infection among symptomatic patients belonging to the upper socioeconomic segment of the population appears to be markedly lower. The lowest prevalence in young patients is expected to result in future decrease in HP prevalence.