Researcher:
Akdemir, Eyüb Yaşar

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Doctor

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Eyüb Yaşar

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Akdemir

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Akdemir, Eyüb Yaşar

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Now showing 1 - 5 of 5
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    Publication
    Radionecrosis: pandora's box
    (Elsevier Ireland Ltd, 2021) N/A; N/A; N/A; N/A; N/A; Bölükbaşı, Yasemin; Samancı, Mustafa Yavuz; Akdemir, Eyüb Yaşar; Peker, Selçuk; Faculty Member; Faculty Member; Doctor; Faculty Member; School of Medicine; School of Medicine; N/A; School of Medicine; Koç University Hospital; 216814; 275252; N/A; 11480
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    PublicationOpen Access
    Surveying the adaptations during the COVID-19 outbreak in Turkish radiotherapy practice
    (Kare Yayıncılık, 2021) Topkan, Erkan; Sezen, Duygu; Selek, Uğur; Akdemir, Eyüb Yaşar; Şenyürek, Şükran; Durankuş, Nilüfer Kılıç; Bölükbaşı, Yasemin; Faculty Member; Faculty Member; Doctor; Faculty Member; School of Medicine; Koç University Hospital; 170535; 27211; N/A; N/A; N/A; 216814
    Objective: we aimed to assess how Turkish Radiation Oncology departments responded to the COVID-19 out-break and to what extent adapted their routine practice per recent guidelines and recommendations. Methods: in late March 2020, a national survey was designed for Turkish radiation oncologists who were actively practicing and members of the Turkish Society for Radiation Oncology (TSRO). The survey created with an online survey program (www.SurveyMonkey.com), including 28 focused items. It was sent to all members of the TSRO on April 4th 2020. Results: of responders, 17% noted to already complete these arrangements even before the first case announced. All of the responders declared that their team members, including the secretaries, nurses, and radiation therapists in the clinic, worked with appropriate protective equipment. While one-third of the centers (35%) stated to implement a weekly shift, the other 1/3 (29%) chose to use daily shifts for social distancing and decreasing staff contact. Sixty-two percent of all responders indicated that multidisciplinary tumor boards discontinued, and the remaining 38% stated to continue with online video conferencing programs (65%) or meeting in large rooms with a limited number of attendees social distancing (35%). Conclusion: our survey revealed the importance of early precautions, communication by other Radiation Oncology Departments, following published guidelines during the COVID-19 pandemic, and the importance of using web-based applications for multidisciplinary tumor boards.
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    PublicationOpen Access
    Vaginal cuff brachytherapy practice in endometrial cancer patients: a report from the Turkish Oncology Group
    (Termedia Publishing, 2021) Önal, Cem; Özsaran, Zeynep; Yıldız, Ferah; Bölükbaşı, Yasemin; Selek, Uğur; Şenyürek, Şükran; Akdemir, Eyüb Yaşar; Faculty Member; Faculty Member; Doctor; School of Medicine; Koç University Hospital; 216814; 27211; N/A; N/A
    Purpose: the American Brachytherapy Association is attempting to develop standards for delivering brachytherapy, although differences in practice have been reported in the literature. This study evaluated vaginal cuff brachytherapy (VBT) practice and quality of life-related recommendations among Turkish radiation oncologists. Material and methods: a nationwide web-based 17-item survey was distributed to the members of the Turkish Society for Radiation Oncology. These members received e-mail notifications, and a link was posted on the Turkish Society for Radiation Oncology internet site to solicit voluntary responses The survey addressed the simulation processes, target volume, prescribed dose, delivery schedules, and recommendations related to vaginal side effects. Results: fifty-seven radiation oncologists responded to the survey. The most used dose fraction schemes for adjuvant VBT were 7 Gy x 3 fractions (30%), 5.5 Gy x 5 fractions (26%), and 6 Gy x 5 fractions (28%). The preferred VBT scheme was 5 Gy x 3 fractions (50%) when the external beam radiotherapy (EBRT) dose was 45 Gy external radiotherapy, while the preferred schemes were 6 Gy x 3 fractions (30%) or 5 Gy x 3 fractions (32%) when the external radiotherapy dose was increased to 50.4 Gy. One-half of the respondents delivered VBT twice a week, and the dose was prescribed to 0.5 cm from vaginal mucosa by 86% of the respondents. There was no common definition for the dose prescription length, which was defined as 3 cm from the vaginal cuff in 33% of responses and as 4 cm in 35% of responses. For serous and clear cell histological types, 38% of the respondents targeted ""full cylinder length"". To prevent vaginal side effects, 78% of the respondents recommended using a vaginal dilator and/or sexual intercourse after VBT. Conclusions: this survey revealed variations in the clinical practice of VBT among Turkish radiation oncologists, which suggests that standardization is necessary.
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    PublicationOpen Access
    Increased levels of anxiety, depression, and secondary trauma in radiation oncologists during COVID-19 pandemic: a preliminary report from Turkey
    (Kare Yayıncılık, 2021) Albayrak, Yakup; Potas, Nihan; Topkan, Erkan; Durankuş, Nilüfer Kılıç; Bölükbaşı, Yasemin; Sezen, Duygu; Akdemir, Eyüb Yaşar; Şenyürek, Şükran; Selek, Uğur; Faculty Member; Faculty Member; Doctor; Faculty Member; School of Medicine; Koç University Hospital; N/A; 216814; 170535; N/A; N/A; 27211
    Objective:we surveyed the anxiety, depression, and secondary trauma levels of Turkish Radiation Oncologists related with COVID pandemics. Methods: an anonymous online questionnaire survey was created to evaluate levels of depression, anxiety, and secondary trauma among Turkish Radiation Oncologists. The survey included demographics and occupational status, Secondary Traumatic Stress Scale (STSSS), The Beck Depression Inventory (BDI), The Beck Anxiety Inventory (BAI), and State-Trait Anxiety Inventory (STAI). Results: seventy-two respondents provided the power of about 91.4% for the significance level of 0.05. The variance homogeneity was checked by the Levene test, the effect of COVID-19 on psychology is higher in the group of >19 (9.02 +/- 0.820), as well as the effect of social isolation (8.02 +/- 1.622), the STSS scores (34.28 +/- 9.062), the STAIS scores (60.46 +/- 5.296), the STAIT scores (82.21 +/- 9.298), the BDI scores (22.68 +/- 2.788), and the BAI scores (21.04 +/- 9.321). The multiple regressions to estimate BDI revealed statistically significant effects in STAIS, BAI, and STAIT. There is a significant correlation between STSS, STAIS, STAIT, BDI, BAI, the effect of COVID-19 on psychology, and the effect of social isolation. Conclusion: we have established one of the first studies demonstrating the effects of COVID-19 pandemic on depression, anxiety levels, and secondary trauma on a special physician population, the Radiation Oncologists, who specifically do not directly take part in COVID19 management.
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    PublicationOpen Access
    Double isocenter optimization with HD-MLC linear accelerator to treat extended fields in patients with head and neck cancers
    (Bakis Productions LTD, 2021) Küçük, Ahmet; Topkan, Erkan; Selek, Uğur; Bölükbaşı, Yasemin; Durankuş, Nilüfer Kılıç; Sezen, Duygu; Sağlam, Yücel; Atasoy, Ali İhsan; Karaköse, Fatih; Alpan, Vildan; Akdemir, Eyüb Yaşar; Şenyürek, Şükran; Faculty Member; Faculty Member; Faculty Member; Doctor; Doctor; School of Medicine; Koç University Hospital; 27211; 216814; N/A; 170535; N/A; N/A; N/A; N/A; N/A; N/A
    Purpose: for departments with a congested patient burden or with a limited number of eligible LINACs, we investigated whether LINACS dedicated for SRS-SBRT with limited field high-definition (HD) multi-leaf collimator (MLC) could help to carry this load, and utilized a double-isocenter (DI) optimization with a limited field size of HD-MLC to defeat the craniocaudal field size restriction to match treated plans in a wide-field MLC LINAC for head and neck cancer patients. Methods: fourteen patients with locally advanced head and neck cancers were included, previously treated with simultaneous integrated boost volumetric modulated arc treatment (VMAT) in 33 fractions of clinical target volumes (CTV) of 70Gy, 63Gy, and 57Gy, via single isocenter (SI) plans in Millennium MLC-120 of Varian Trilogy. The DI plans were generated on Pinnacle TPS to be delivered in HD 120 leaves MLC on Varian TrueBeam. The organs at risk (OAR) doses and the prescription volume parameters were compared. Results: DI plans in HD-MLC LINACs were successfully matching the previously treated plans for OAR and CTV constraints. The CI (1.18 versus 1.26; p=0.004) and HI (0.23 versus 0.29; p<0.001) were significantly improved with DI, while the MUs (1321.5 versus 800.3; p<0.001) and the treatment delivery times (6.1 versus 3.7 min; p<0.001) per fraction increased modestly with DI compared to SI, respectively. Conclusions: we revealed that DI optimization plans prepared for HD-MLC could effectively accomplish our goal dosimetrically in locoregionally advanced head and neck cases, despite a modest increase in the MU and treatment delivery times per fraction. This technique may provide an alternative in case of downtimes of standard MLC systems or a standalone treatment machine in case of high volumes requiring extended-field IMRT procedures, or possibly shorten the lengthy waiting times in facilities with limited SRS or SBRT patients.