Researcher:
Yüce, Murat Necdet

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Undergraduate Student

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Murat Necdet

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Yüce

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Yüce, Murat Necdet

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    Publication
    Post-activation depression of primary afferents reevaluated in humans
    (Elsevier, 2020) N/A; N/A; N/A; N/A; N/A; N/A; N/A; Özyurt, Mustafa Görkem; Topkara, Betilay; Şenocak, Beatrice Selen; Budan, Abdullah Salih; Yüce, Murat Necdet; Türker, Kemal Sıtkı; PHD Student; PHD Student; Master Student; Undergraduate Student; Undergraduate Student; Faculty Member; Graduate School of Sciences and Engineering; Graduate School of Health Sciences; Graduate School of Sciences and Engineering; School of Medicine; School of Medicine; School of Medicine; N/A; N/A; N/A; N/A; N/A; N/A; 6741
    Amplitude variation of Hoffmann Reflex (H-reflex) was used as a tool to investigate many neuronal networks. However, H-reflex itself is a subject to intrinsic changes including post-activation depression (P-AD). We aimed to investigate P-AD and its implication on motor control in humans. Upon tibial nerve stimulation in 23 healthy participants, peak-to-peak amplitude change of H-reflex was investigated using surface electromyography (SEMG) of soleus muscle. Variety of stimulus intensities, interstimulus intervals (ISIs), voluntary contraction levels/types and force recording were used to investigate the nature of P-AD. We have shown that P-AD was significantly stronger in the shorter ISIs. The only exception was the ISI of 200 msecs which had a weaker P-AD than some of the longer ISIs. Sudden muscle relaxation, on the other hand, further increased the effectiveness of the ongoing P-AD. Moreover, P-AD displayed its full effect with the first stimulus when there was no muscle contraction and was efficient to reduce the muscle force output by about 30%. These findings provide insight about the variations and mechanism of P-AD and could lead to improvements in diagnostic tools in neurological diseases.