Researcher:
Arslan, Harun

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Doctor

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Harun

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Arslan

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Arslan, Harun

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20201

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Researcher Of Publications: search.filters.isAuthorOfPublication.f75fc927-7c19-4ca2-946a-d9c0d644442f

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    PublicationOpen Access
    Hiv-associated non hodgkin lymphoma: a case series study from Turkey
    (African Traditional Herbal Medicine Supporters Initiative, 2020) Somay, Kayra; Çöpür, Sidar; Osmanbaşoğlu, Emre; Masyan, Helin; Arslan, Harun; Akay, Olga Meltem; Tekin, Süda; Ferhanoğlu, Ahmet Burhan; Researcher; Faculty Member; Faculty Member; School of Medicine; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; N/A; N/A; 18320
    Background: human immunodeficiency virus (HIV) is a global health concern with major risks for opportunistic infections and predisposition to malignancies including Kaposi sarcoma associated with Human Herpes Virus-8 (HHV-8) and non-Hodgkin lymphoma (NHL) commonly associated with Epstein Barr Virus (EBV). Although the exact mechanisms of predisposition to certain malignancies are unclear, HIV (+) cancer patients typically have poorer prognosis. Materials and methods: we included all five HIV positive NHL patients receiving antiretroviral therapy (ART) and chemotherapy in our clinic and aim to determine their follow-up outcomes associated with ART. Results: the use of ART in conjunction with chemotherapy regimens lead to better therapeutic outcome in our cases with no mortality over three years of follow-up despite high rates of poor prognostic factors and studies demonstrating 1-year survival rates of approximately 30% in HIV-associated lymphoma. No significant adverse effect has been recorded. Conclusion: we recommend use of ART along with chemotherapy regimens in HIV positive lymphoma patients for better treatment response.