Publication: Meso-2,3-dimercaptosuccinic acid: from heavy metal chelation to CdS quantum dots
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Özen, Can
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NO
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Abstract
DMSA (meso-2,3-dimercaptosuccinic acid) a prescription drug and a heavy-metal chelating agent, is shown to act both as a sulfur source and a capping agent in the aqueous synthesis of CdS quantum dots under mild conditions. Release of sulfur from DMSA depends on the solution pH and the reaction temperature. Combination of 70 C and pH 7.5 was determined as the best reaction conditions for a well-controlled reaction. Changing the SH/Cd ratio from 2.5 to 7 provides QDs emitting from blue to orange with 6–9% quantum yield with respect to Rhodamine 2B. Viability tests performed with HeLa and MCF-7 cell lines indicate a very low cytotoxicity. Mild reaction conditions and biocompatibility makes these particles valuable candidates for bio applications.
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Publisher
Royal Society of Chemistry (RSC)
Subject
Physical chemistry, Material sciences
Citation
Has Part
Source
Journal of Materials Chemistry
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Edition
DOI
10.1039/c2jm15741a