Publication: The influence of melatonin on brain tumors: a comprehensive review
Program
KU-Authors
KU Authors
Co-Authors
Becker, Aline Paixão
Becker, Valesio
Publication Date
Language
Type
Embargo Status
Journal Title
Journal ISSN
Volume Title
Alternative Title
Abstract
Primary brain tumors are a heterogeneous group of neoplasms, originating from glial and other cell types in the central nervous system (CNS). Despite advancements in technology and medicine, the prognosis for malignant brain tumors remains poor. This situation requires novel therapeutic approaches. Melatonin, a hormone produced by the pineal gland, regulates sleep and circadian rhythms. It also possesses various biological functions, such as antioxidant properties, immune modulation, and tumor suppression. This review analyzes existing research on the effects of melatonin on brain tumors, focusing on its therapeutic potential and mechanisms of action, and highlights melatonin's promise as a complementary therapy against adult and pediatric high-grade gliomas.
Source
Publisher
Kare Publ
Subject
Oncology
Citation
Has Part
Source
Türk Onkoloji Dergisi-Turkish Journal of Oncology
Book Series Title
Edition
DOI
10.5505/tjo.2024.4387