Publication:
The relationship between aerobic capacity and left atrial size in healthy young males: an observational study

Thumbnail Image

Departments

School / College / Institute

Organizational Unit
Organizational Unit
SCHOOL OF MEDICINE
Upper Org Unit

Program

KU Authors

Co-Authors

Ozyigit, Tolga

Publication Date

Language

Embargo Status

Journal Title

Journal ISSN

Volume Title

Alternative Title

Abstract

Aerobic capacity, defined as peak oxygen uptake (peakVO(2)), is a marker for aerobic fitness and is associated with left ventricular (LV) systolic and diastolic function. The aim of the study was to explore the relation between left atrial (LA) volume index (LAVI) and aerobic capacity in healthy young male adults. One hundred three healthy young male subjects (mean age: 34.2 +/- 5.5years) were consecutively included in the study. All subjects underwent echocardiography to assess LAVI, LV systolic and diastolic functions. Aerobic capacity was assessed by cardiopulmonary exercise testing. All patients had normal left ventricular ejection fraction (LVEF). One hundred one subjects had normal LAVI (<= 34 mL/m(2)) while 2 subjects had mildly increased LAVI (35-41 mL/m(2)). Mean peakVO(2) predicted was 82.2 +/- 14.4%. 64subjects (62.1%) had a peakVO(2) < 85% of age-predicted and sex-predicted values and they had higher LAVI compared to those who had a peakVO(2) higher than 85% of age-predicted and sex-predicted values (22.0 +/- 4.8 mL/m(2) vs 20.3 +/- 4.1 mL/m(2), P = .055). Notably, only LAVI showed a significant correlation with peakVO(2) and predicted breathing reserve (BR), while anaerobic threshold correlated with both LAVI and LVEF. Age was also a significant factor, negatively impacting peakVO(2) (r = -0.265, P = .007) and predicted BR (r = -0.282, P = .004). Multivariate analysis revealed that both LAVI and age were independent predictors of peakVO(2) and predicted BR. This study suggests that LAVI can be a valuable indicator of aerobic capacity in apparently healthy young males.

Source

Publisher

Lippincott Williams and Wilkins

Subject

Medicine, General, Internal

Citation

Has Part

Source

Medicine

Book Series Title

Edition

DOI

10.1097/MD.0000000000038931

item.page.datauri

Link

Rights

Copyrights Note

Endorsement

Review

Supplemented By

Referenced By

3

Views

6

Downloads

View PlumX Details