Multicentric donor survey 20 years after donor hepatectomy

Abstract

Background: We implemented a multicenter interview with donors to investigate quality of life (QoL) up to 20 years following donation.

Methods: Data were collected retrospectively. Complications were graded according to the Dindo–Clavien classification.

Results: The median follow-up was 16.1 years. Of 485 donors, 272 responded (56.1%). The majority (>90%) reported excellent/good overall health and a positive or no impact of donation on professional life. Length of stay (LOS) was associated with the impact on professional life and return to baseline functionality (both p = 0.046). Major complications were not associated with current physical condition or return to baseline normalcy (p = 0.06). Seventy-five donors (27.5%) reported being unsure about or unwilling to donate again. None of the evaluated parameters were associated with the willingness to donate again. Faster return to baseline functionality and more positive impacts on professional life were reported in the last decade, likely due to lower complication rates (all p < 0.001).

Conclusion: This is the longest follow-up report after living liver donation among German and Turkish populations. Although subject to recall bias, LOS was associated with negative impacts on professional life and return to baseline functionality. Regret feelings were higher than those reported in the literature. These long-term effects should be incorporated into donor discussions.