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Urinary neutrophil gelatinase-associated lipocalin is associated with preeclampsia in a cohort of Turkish women

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dc.contributor.coauthorYüksel, Semra
dc.contributor.coauthorÖzyürek, Şefik Eser
dc.contributor.coauthorAcar, Deniz Kanber
dc.contributor.coauthorÖzdemir, Çağdaş
dc.contributor.coauthorKıyak, Hüseyin
dc.contributor.coauthorGedikbaşı, Ali
dc.contributor.departmentKUH (Koç University Hospital)
dc.contributor.kuauthorÇekiç, Sebile Güler
dc.contributor.kuprofileDoctor
dc.contributor.schoolcollegeinstituteKUH (KOÇ UNIVERSITY HOSPITAL)
dc.contributor.yokidN/A
dc.date.accessioned2024-11-09T23:44:10Z
dc.date.issued2019
dc.description.abstractPurpose: We investigated the optimal cut-off level for urinary neutrophil gelatinase-associated lipocalin (NGAL) in preeclamptic patients to confirm the diagnosis. Methods: Urinary NGAL concentrations were measured by specific enzyme-linked immunosorbent assay (ELISA). Results: Patients with preeclampsia had significantly higher urinary NGAL concentrations than controls (mean: 387 ng/ml vs. 188 ng/ml, respectively; P< 0.001). Using a cutoff value 252 ng/ml for urinary NGAL to confirm diagnosis of preeclampsia, sensitivity, and specificity were 92% and 91%, respectively. Conclusion: Urinary NGAL concentrations were significantly elevated in women with preeclampsia versus normotensive controls.
dc.description.indexedbyWoS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue3
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.volume38
dc.identifier.doi10.1080/10641955.2019.1621887
dc.identifier.issn1064-1955
dc.identifier.linkhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85066605793&doi=10.1080%2f10641955.2019.1621887&partnerID=40&md5=c8947324b04c3d55f3aae961ee01a70e
dc.identifier.scopus2-s2.0-85066605793
dc.identifier.urihttp://dx.doi.org/10.1080/10641955.2019.1621887
dc.identifier.urihttps://hdl.handle.net/20.500.14288/13615
dc.keywordsPreeclampsia
dc.keywordsNeutrophil gelatinase associated lipocalin
dc.keywordsSevere preeclampsia
dc.keywordsPreeclampsia diagnosis
dc.languageEnglish
dc.publisherTaylor & Francis
dc.sourceHypertension in Pregnancy
dc.subjectObstetrics
dc.subjectGynecology
dc.subjectPhysiology
dc.subjectPeripheral vascular disease
dc.titleUrinary neutrophil gelatinase-associated lipocalin is associated with preeclampsia in a cohort of Turkish women
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.authorid0000-0002-1632-1170
local.contributor.kuauthorÇekiç, Sebile Güler
local.publication.orgunit1KUH (KOÇ UNIVERSITY HOSPITAL)
local.publication.orgunit2KUH (Koç University Hospital)
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