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Comparison of methotrexate and Azathioprine as the first steroid-sparing immunosuppressive agent in patients with Takayasu's Arteritis

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SCHOOL OF MEDICINE

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Kaymaz-Tahra, Sema
Tsechelidis, Ozun Bayindir
Ince, Burak
Isik, Ozlem Ozdemir
Kutu, Muhammet Emin
Karakas, Ozlem
Yildirim, Tuba Demirci
Ademoglu, Zeliha
Ediboglu, Elif Durak
Uludogan, Burcu Ceren Ekti

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Background Conventional disease-modifying anti-rheumatic drugs (cDMARDs) are recommended in addition to glucocorticoids (GC) for all active Takayasu's arteritis (TAK) patients as the first-line therapy.However, there is limited data comparing cDMARDs as the first-line immunosuppressive (IS) treatment. Objectives In this study, we aimed to compare the outcomes of methotrexate (MTX) and azathioprine (AZA), which were used most frequently as the first-line cDMARDs in TAK patients.

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Wiley

Subject

Rheumatology

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ARTHRITIS and RHEUMATOLOGY

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