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Long-term outcomes of conventional core decompression for osteonecrosis of the femoral head in systemic lupus erythematosus: a single-center retrospective study

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SCHOOL OF MEDICINE

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Demirel, M.
Ersin, M.
Ekinci, M.
Mert, L.
Koyuncu, D.

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OBJECTIVE: Although the thera-peutic efficacy of conventional core decompres-sion (CD) for the early-stage osteonecrosis (ON) has been widely investigated in the literature, no study to date has specifically focused on its therapeutic effect on the long-term outcome of ON of the femoral head (ONFH) in systemic lu-pus erythematosus (SLE). This study aimed to provide a long-term survival analysis of all hips that underwent conventional CD for the manage-ment of ONFH in a consecutive case series of patients with SLE.PATIENTS AND METHODS: Sixteen hips of 10 consecutive SLE patients that underwent conventional CD for the management of ONFH in a single tertiary referral center were retrospec-tively identified and included in the study. After a retrospective chart review, several clinical and radiological data were recorded. RESULTS: All the hips treated with CD were stage I or IIA sclerotic and/or cystic based on the classification system of Ficat. Only the 2 hips of 1 patient (12.5%) survived both clinically and radiographically. The median overall surviv-al for all hips after CD was 80 months (95% CI, 60-100). The 5-, 10-, and 15-year survival rates of hip joints following CD were 63%, 31%, and 12.5%, respectively (CI 95% 63.567 to 133.058 months).CONCLUSIONS: Conventional CD may not be effective in preventing the progression of pre-collapse ONFH to collapse and eventually end-stage osteoarthritis requiring arthroplasty in patients with SLE.

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Verduci Publisher

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Pharmacology, Pharmacy

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European Review for Medical and Pharmacological Sciences

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10.26355/eurrev_202303_31546

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