Publication:
Long-term outcomes of conventional core decompression for osteonecrosis of the femoral head in systemic lupus erythematosus: a single-center retrospective study

dc.contributor.coauthorDemirel, M.
dc.contributor.coauthorErsin, M.
dc.contributor.coauthorEkinci, M.
dc.contributor.coauthorMert, L.
dc.contributor.coauthorKoyuncu, D.
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorKılıçoğlu, Önder
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2025-01-19T10:32:28Z
dc.date.issued2023
dc.description.abstractOBJECTIVE: Although the thera-peutic efficacy of conventional core decompres-sion (CD) for the early-stage osteonecrosis (ON) has been widely investigated in the literature, no study to date has specifically focused on its therapeutic effect on the long-term outcome of ON of the femoral head (ONFH) in systemic lu-pus erythematosus (SLE). This study aimed to provide a long-term survival analysis of all hips that underwent conventional CD for the manage-ment of ONFH in a consecutive case series of patients with SLE.PATIENTS AND METHODS: Sixteen hips of 10 consecutive SLE patients that underwent conventional CD for the management of ONFH in a single tertiary referral center were retrospec-tively identified and included in the study. After a retrospective chart review, several clinical and radiological data were recorded. RESULTS: All the hips treated with CD were stage I or IIA sclerotic and/or cystic based on the classification system of Ficat. Only the 2 hips of 1 patient (12.5%) survived both clinically and radiographically. The median overall surviv-al for all hips after CD was 80 months (95% CI, 60-100). The 5-, 10-, and 15-year survival rates of hip joints following CD were 63%, 31%, and 12.5%, respectively (CI 95% 63.567 to 133.058 months).CONCLUSIONS: Conventional CD may not be effective in preventing the progression of pre-collapse ONFH to collapse and eventually end-stage osteoarthritis requiring arthroplasty in patients with SLE.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue5
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume27
dc.identifier.doi10.26355/eurrev_202303_31546
dc.identifier.issn1128-3602
dc.identifier.quartileQ2
dc.identifier.scopus2-s2.0-85150666267
dc.identifier.urihttps://doi.org/10.26355/eurrev_202303_31546
dc.identifier.urihttps://hdl.handle.net/20.500.14288/26423
dc.identifier.wos959553700016
dc.keywordsOsteonecrosis
dc.keywordsOsteonecrosis of the femoral head
dc.keywordsSystemic lupus erythematosus
dc.keywordsCore decompression
dc.keywordsSurvival rate
dc.keywordsSurvivorship analysis
dc.language.isoeng
dc.publisherVerduci Publisher
dc.relation.ispartofEuropean Review for Medical and Pharmacological Sciences
dc.subjectPharmacology
dc.subjectPharmacy
dc.titleLong-term outcomes of conventional core decompression for osteonecrosis of the femoral head in systemic lupus erythematosus: a single-center retrospective study
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorKılıçoğlu, Önder
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit2School of Medicine
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