Obstetric Outcomes of Women With Elisa Positivity For HBV, HCV, or HIV

Abstract

ELISA positivity for Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), and Human Immunodeficiency Virus (HIV) may be associated with negative obstetric outcomes. The aim of this study is to compare the pregnancy complication rates of pregnant women based on ELISA positivity. In this retrospective study, the obstetric outcomes of ELISA -positive and ELISA-negative pregnant women admitted to the delivery room unit of Kanuni Sultan Suleyman Training and Research Hospital between January 2014 and December 2014 were examined. Patients were grouped into two categories based on ELISA positivity or negativity for HBV, HCV, and HIV. In the study, 380 ELISA-positive and 294 ELISA-negative pregnant women were analyzed. The demographic characteristics of both groups were similar. No statistically significant differences were observed between the two groups regarding average age, delivery method, premature birth, preterm membrane rupture (PROM), gestational diabetes mellitus (GDM), preeclampsia, intrahepatic cholestasis of pregnancy (ICP), poly/oligohydramnios, placenta previa, and congenital anomaly rates. The rates of fetal growth restr iction (FGR), gestational hypertension (GHT), and increased pregnancy loss in the ELISA-positive group were found to be significantly higher than those in the ELISA - negative group. In our study, we observed that the FGR and GHT rates in the ELISA -positive group were significantly higher than those in the ELISA-negative pregnant women, and their average birth weight was significantly lower. Therefore, we recommend that pregnancy follow-up for patients with positive serology be evaluated from these aspects.