Publication:
Type-specific analysis of morphometry of dendrite spines of mice

dc.contributor.coauthorFong L.
dc.contributor.coauthorTasky T.N.
dc.contributor.coauthorHurdal M.K.
dc.contributor.coauthorBeg M.F.
dc.contributor.coauthorMartone M.E.
dc.contributor.coauthorRatnanather J.T.
dc.contributor.departmentDepartment of Mathematics
dc.contributor.kuauthorCeyhan, Elvan
dc.contributor.schoolcollegeinstituteCollege of Sciences
dc.date.accessioned2024-11-09T23:18:32Z
dc.date.issued2007
dc.description.abstractIn this article, we analyze the morphometric measures of dendrite spines of mice derived from electron tomography images for different spine types based on pre-assigned categories. The morphometric measures we consider include the metric distance, volume, surface area, and length of dendrite spines of mice. The question of interest is how these morphometric measures differ by condition of mice; and how the metric distance relates to volume, surface area, length, and condition of mice. The Large Deformation Diffeomorphic Metric Mapping algorithm is the tool we use to obtain the metric distances that quantize the morphometry of binary images of dendrite spines with respect to a template spine. We demonstrate that for the values not adjusted for scale metric distances and other morphometric measures are significantly different between the conditions. The morphometric measures (rather than the mice condition) explain almost all the variation in metric distances. Since size (or scale) dominates the other variables in variation, we adjust metric distances and other morphometric measures for scale. We demonstrate that the scaled metric distances and other scaled morphometric variables still differ for condition, and scaled metric distances depend most significantly on scaled morphometric measures. The methodology used is also valid for morphometric measures of other organs or tissues and metric distances other than LDDMM.
dc.description.indexedbyScopus
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipIEEE Region 8
dc.description.sponsorshipIEEE Croatia Section - CAS and SP Society Chapter
dc.description.sponsorshipIEEE Croatia Section - Computer Society Chapter
dc.identifier.doi10.1109/ISPA.2007.4383655
dc.identifier.isbn9789-5318-4116-0
dc.identifier.quartileN/A
dc.identifier.scopus2-s2.0-47949114427
dc.identifier.urihttps://doi.org/10.1109/ISPA.2007.4383655
dc.identifier.urihttps://hdl.handle.net/20.500.14288/10392
dc.keywordsConformal mapping
dc.keywordsDendrites (metallography)
dc.keywordsDiagnostic radiography
dc.keywordsElectric impedance tomography
dc.keywordsImage enhancement
dc.keywordsMedical imaging
dc.keywordsSignal processing
dc.keywordsTomography
dc.keywordsElectron tomographies
dc.keywordsMapping algorithms
dc.keywordsMetric distances
dc.keywordsMorphometric variables
dc.keywordsMorphometry
dc.keywordsSurface areas
dc.keywordsTheorem proving
dc.language.isoeng
dc.publisherIEEE
dc.relation.ispartofISPA 2007 - Proceedings of the 5th International Symposium on Image and Signal Processing and Analysis
dc.subjectMathematics
dc.titleType-specific analysis of morphometry of dendrite spines of mice
dc.typeConference Proceeding
dspace.entity.typePublication
local.contributor.kuauthorCeyhan, Elvan
local.publication.orgunit1College of Sciences
local.publication.orgunit2Department of Mathematics
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relation.isOrgUnitOfPublication.latestForDiscovery2159b841-6c2d-4f54-b1d4-b6ba86edfdbe
relation.isParentOrgUnitOfPublicationaf0395b0-7219-4165-a909-7016fa30932d
relation.isParentOrgUnitOfPublication.latestForDiscoveryaf0395b0-7219-4165-a909-7016fa30932d

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