Publication: Wound healing effects of methanol extract of Laurocerasusofficinalis roem
Program
KU-Authors
KU Authors
Co-Authors
Ayla, S.
Okur, M. E.
Gunal, M. Y.
Ozdemir, E. M.
Polat, D. Cicek
Yoltas, A.
Biceroglu, O.
Publication Date
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Type
Embargo Status
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Volume Title
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Abstract
Laurocerasus officinalis Roem. (syn: Prunus laurocerasus L.) is a member of Rosaceae family. We investigated the antimicrobial and antioxidant activity of L. officinalis Roem in wound healing both in vivo and in vitro using an excisional wound model model in mice. We used four groups of eight mice as follows: untreated (control), empty gel, extract +gel (L. officinalis +gel), and Madecassol (R) groups. All treatments were applied topically once daily. The scar area, percentage wound closure and epithelization time were measured. L. officinalis promoted wound healing and increased granulation tissue, epidermal regeneration and angiogenesis. L. officinalis extract, which is known for its antioxidant and antimicrobial activities, may be useful for promoting wound healing.
Source
Publisher
Taylor & Francis
Subject
Biotechnology, Applied microbiology, Cell biology
Citation
Has Part
Source
Biotechnic and Histochemistry
Book Series Title
Edition
DOI
10.1080/10520295.2018.1539242