Publication: Considerations for clinical trials testing radiotherapy combined with immunotherapy for metastatic disease
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Co-Authors
Verma, Vivek
He, Kewen
Abana, Chike O.
Barsoumian, Hampartsaum
Ning, Matthew S.
Tang, Chad
Hurmuz, Pervin
Puebla-Osorio, Nahum
Chen, Dawei
Tendler, Irwin
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Abstract
Metastatic cancer is inherently heterogeneous, and patients with metastatic disease can experience vastly different oncologic outcomes depending on several patient-and disease specific characteristics. Designing trials for such a diverse population is challenging yet necessary to improve treatment outcomes for metastatic-previously thought to be incurable-disease. Here we review core considerations for designing and conducting clinical trials involving radiation therapy and immunotherapy for patients with metastatic cancer.
Source
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Elsevier
Citation
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Source
Seminars in Radiation Oncology
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DOI
10.1016/j.semradonc.2021.02.005
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