Publication:
Considerations for clinical trials testing radiotherapy combined with immunotherapy for metastatic disease

dc.contributor.coauthorVerma, Vivek
dc.contributor.coauthorHe, Kewen
dc.contributor.coauthorAbana, Chike O.
dc.contributor.coauthorBarsoumian, Hampartsaum
dc.contributor.coauthorNing, Matthew S.
dc.contributor.coauthorTang, Chad
dc.contributor.coauthorHurmuz, Pervin
dc.contributor.coauthorPuebla-Osorio, Nahum
dc.contributor.coauthorChen, Dawei
dc.contributor.coauthorTendler, Irwin
dc.contributor.coauthorComeaux, Nathan
dc.contributor.coauthorQuynh-Nhu Nguyen
dc.contributor.coauthorChang, Joe Y.
dc.contributor.coauthorWelsh, James W.
dc.contributor.departmentSchool of Medicine
dc.contributor.facultymemberYes
dc.contributor.kuauthorSezen, Duygu
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-09T23:21:47Z
dc.date.issued2021
dc.description.abstractMetastatic cancer is inherently heterogeneous, and patients with metastatic disease can experience vastly different oncologic outcomes depending on several patient-and disease specific characteristics. Designing trials for such a diverse population is challenging yet necessary to improve treatment outcomes for metastatic-previously thought to be incurable-disease. Here we review core considerations for designing and conducting clinical trials involving radiation therapy and immunotherapy for patients with metastatic cancer.
dc.description.fulltextNo
dc.description.harvestedfromManual
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.openaccessNO
dc.description.peerreviewstatusN/A
dc.description.publisherscopeInternational
dc.description.readpublishN/A
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipCancer Center Support (Core) Grant from the National Cancer Institute, National Institutes of Health [P30 CA016672], Supported in part by Cancer Center Support (Core) Grant P30 CA016672 from the National Cancer Institute, National Institutes of Health, to The University of Texas MD Anderson Cancer Center.
dc.description.versionN/A
dc.identifier.doi10.1016/j.semradonc.2021.02.005
dc.identifier.eissn1532-9461
dc.identifier.embargoN/A
dc.identifier.grantnoP30 CA016672
dc.identifier.issn1053-4296
dc.identifier.pubmed34090648
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-85102076098
dc.identifier.urihttps://doi.org/10.1016/j.semradonc.2021.02.005
dc.identifier.urihttps://hdl.handle.net/20.500.14288/10954
dc.identifier.wos000658149000007
dc.keywordsReceiving combined immunotherapy
dc.keywordsBody radiation-therapy
dc.keywordsCost-effectiveness
dc.keywordsCTLA-4 blockade
dc.language.isoeng
dc.publisherElsevier
dc.relation.affiliationKoç University
dc.relation.collectionKoç University Institutional Repository
dc.relation.ispartofSeminars in Radiation Oncology
dc.relation.openaccessN/A
dc.rightsN/A
dc.subjectOncology
dc.subjectRadiology, nuclear medicine and medical imaging
dc.titleConsiderations for clinical trials testing radiotherapy combined with immunotherapy for metastatic disease
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorSezen, Duygu
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