Publication:
Oncogenic mechanisms in renal insufficiency

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dc.contributor.coauthorVolovat, S.R.
dc.contributor.coauthorVolovat, C.
dc.contributor.coauthorMiron, I.
dc.contributor.coauthorGoldsmith, D.
dc.contributor.coauthorLungulescu, C.
dc.contributor.coauthorBadarau, S.C.
dc.contributor.coauthorCovic A.
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorKanbay, Mehmet
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-09T12:13:49Z
dc.date.issued2021
dc.description.abstractThe prevalence of both cancer and end-stage renal disease is increasing. In addition, medical advances have meant increased survival rates for both diseases. Many chemotherapeutics are renally excreted, and conversely, renal insufficiency promotes a pro-neoplastic state, including genitourinary and other cancers. Dialysis prolongs life while increasing cancer risk. Proposed oncogenic mechanisms include immune dysfunction, chronic inflammation, changes in gut microbiota and stimulation of the renin-angiotensin system. This review summarizes current concepts in the relationship between cancer and renal insufficiency.
dc.description.fulltextYES
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue2
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipN/A
dc.description.versionPublisher version
dc.description.volume14
dc.identifier.doi10.1093/ckj/sfaa122
dc.identifier.eissn2048-8513
dc.identifier.embargoNO
dc.identifier.filenameinventorynoIR03550
dc.identifier.issn2048-8505
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-85126333593
dc.identifier.urihttps://hdl.handle.net/20.500.14288/1257
dc.identifier.wos642298900007
dc.keywordsCancer
dc.keywordsCarcinogenesis
dc.keywordsEnd-stage renal disease
dc.keywordsMalignancy
dc.keywordsRenal transplant
dc.language.isoeng
dc.publisherOxford University Press (OUP)
dc.relation.grantnoNA
dc.relation.ispartofClinical Kidney Journal
dc.relation.urihttp://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/10408
dc.subjectUrology and nephrology
dc.titleOncogenic mechanisms in renal insufficiency
dc.typeReview
dspace.entity.typePublication
local.contributor.kuauthorKanbay, Mehmet
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit2School of Medicine
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relation.isOrgUnitOfPublication.latestForDiscoveryd02929e1-2a70-44f0-ae17-7819f587bedd
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relation.isParentOrgUnitOfPublication.latestForDiscovery17f2dc8e-6e54-4fa8-b5e0-d6415123a93e

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