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Permanent URI for this collectionhttps://hdl.handle.net/20.500.14288/3
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Publication Metadata only Development and psychometric analysis of care needs scale for mothers of children with congenital heart disease(Elsevier Inc., 2024) Ay, Ayse; Saridag, Kubra Nur Kabakci; Semerci, Remziye; School of NursingPurpose: This cross-sectional study aimed to create and evaluate a care needs scale for mothers of children with congenital heart disease (CHD) to determine its psychometric properties. Design and methods: This methodological research was conducted with 155 mothers whose children were diagnosed with CHD and were treated at a university hospital. The study's methodology included scale development, specialist opinions, and a pilot test. Data analysis involved descriptive statistics, exploratory and con firmatory factor analyses, and reliability assessments. Results: The 11 -item scale was created using component analysis, expert comments, and pilot testing. It was divided into two categories: Information Needs Regarding Disease and Treatment and Needs Regarding Care. The Exploratory Factor Analysis revealed a 2 -factor structure, explaining 41.5% of the variance. Reliability analysis showed reliable dimensions, and Tukey's scalability test indicated the scale requires separate dimension evaluation. The model fi t indices were obtained as CMIN/DF (72.751/41) =1.774, GFI = 0.925, IFI = 0.923, TLI = 0.893, CFI = 0.920, RMSEA = 0.071, SRMR = 0.063. The Cronbach's alpha coef ficient for subdimension 1 was 0.758, and for subdimension 2 was 0.678, indicating reliable dimensions. Conclusion: The developed scale provides a valuable tool for assessing the care needs of mothers of children with CHD, contributing to enhancing maternal support programs in pediatric cardiology clinics. Practice implications: Assessment of the care needs of mothers who have children with CHD is promising for the development of educational programs on this subject and to ensure the competence of mothers for care.Publication Metadata only Pediatric-onset chronic inflammatory demyelinating polyneuropathy: a multicenter study(Elsevier Science Inc, 2023) Uzan, Gamze Sarikaya; Yuksel, Deniz; Aksoy, Erhan; Oztoprak, Ulkuhan; Canpolat, Mehmet; Ozturk, Selcan; Yildirim, Celebi; Gulec, Ayten; Per, Huseyin; Gumus, Hakan; Okuyaz, Cetin; Direk, Meltem Cobanoullari; Kosmur, Mustafa; Unalp, Aycan; Yilmaz, Unsal; Bektas, Omer; Teber, Serap; Aliyeva, Nargiz; Dundar, Nihal Olgac; Gencpinar, Pinar; Gurkas, Esra; Yilmaz, Sanem Keskin; Kanmaz, Seda; Tekgtil, Hasan; Aksoy, Ayse; Tuncer, Gokcen Oz; Arslan, Elif Acar; Tosun, Ayse; Ayanoglu, Muge; Bodur, Muhittin; Unay, Bulent; Kurul, Semra Hiz; Yis, Uluc; Vural, Atay; Yousefi, Mohammadreza; Kızılırmak, Ali Burak; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); School of Medicine; Graduate School of Health SciencesBackground: To evaluate the clinical features, demographic features, and treatment modalities of pediatric-onset chronic inflammatory demyelinating polyneuropathy (CIDP) in Turkey. Methods: The clinical data of patients between January 2010 and December 2021 were reviewed retrospectively. The patients were evaluated according to the Joint Task Force of the European Federation of Neurological Societies and the Peripheral Nerve Society Guideline on the management of CIDP (2021). In addition, patients with typical CIDP were divided into two groups according to the first-line treatment modalities (group 1: IVIg only, group 2: IVIg + steroid). The patients were further divided into two separate groups based on their magnetic resonance imaging (MRI) characteristics. Results: A total of 43 patients, 22 (51.2%) males and 21 (48.8%) females, were included in the study. There was a significant difference between pretreatment and post-treatment modified Rankin scale (mRS) scores (P < 0.05) of all patients. First-line treatments include intravenous immunoglobulin (IVIg) (n = 19, 4 4.2%), IVIg + steroids (n = 20, 46.5%), steroids (n = 1, 2.3%), IVIg + steroids + plasmapheresis (n = 1, 2.3%), and IVIg + plasmapheresis (n = 1, 2.3%). Alternative agent therapy consisted of azathioprine (n = 5), rituximab (n = 1), and azathioprine + mycophenolate mofetil + methotrexate (n = 1). There was no difference between the pretreatment and post-treatment mRS scores of groups 1 and 2 (P > 0.05); however, a significant decrease was found in the mRS scores of both groups with treatment (P < 0.05). The patients with abnormal MRI had significantly higher pretreatment mRS scores compared with the group with normal MRI (P < 0.05). Conclusions: This multicenter study demonstrated that first-line immunotherapy modalities (IVIg vs IVIg + steroids) had equal efficacy for the treatment of patients with CIDP. We also determined that MRI features might be associated with profound clinical features, but did not affect treatment response.Publication Metadata only Late relapse in neuroblastoma: case report and review of the literature(Bentham Science Publ Ltd, 2023) Kebudi, R.; Koc, B.; Sözmen, Banu Oflaz; School of MedicineBackground: Neuroblastoma is the most common extra-cranial solid tumor in children. The survival rate of relapsed/refractory neuroblastoma is dismal. Late recurrence may occur rarely. Case Presentation: We have, herein, presented a case with stage IV neuroblastoma who relapsed after 11 years and had a subsequent relapse after 15 years from the initial diagnosis, and reviewed cases with late relapsed (after >5 years) neuroblastoma in the literature. The case presented with recurrent disease at the T7 vertebra after 11 years from the initial diagnosis. The patient received surgery, chemotherapy, MIBG treatment, and antiGD2 combined with chemotherapy, and had a further local recurrence in the paravertebral area of the removed T7 vertebra after three years. The patient was operated, received anti-GD2 combined with chemotherapy, and is still alive with no symptoms for 19 months after the last relapse. Conclusion: There is not a well-established treatment regimen for the majority of these patients. MIBG treatment and antiGD2 combined with chemotherapy may be promising options for relapsed/refractory neuroblastoma.Publication Metadata only The effects of child health nursing curriculum-integrated therapeutic activities on therapeutic communication skills of nursing students: non-randomized study(Elsevier Science Inc, 2023) Semerci, Remziye; Semerci, Remziye; Umaç, Eyşan Hanzade; School of Nursing; Graduate School of Health SciencesBackground: Effective therapeutic communication with hospitalized children is increasingly recognized as crucial for child-centered care in all healthcare settings. The quantity and quality of training nurses receive to promote and enhance nurse-child communication are vital. This study aims to evaluate the impact of planned therapeutic communication activities for the Child Health Nursing Course on the therapeutic communication skills of nursing students. Method: A non-randomized study with a pre-test and post-test design was conducted with 28 junior nursing students in Turkey. Data were collected using an 'Information Form' and the 'Therapeutic Communication Skills Scale for Nursing Students'. The Child Health Nursing Course curriculum incorporated lectures with various activity designs to enhance students' therapeutic communication skills. Results: The curriculum-integrated therapeutic activities significantly decreased non-therapeutic communication skills in students, with a large effect size [d: 0.827, 95% CI: (0.393)-(1.296)]. Furthermore, the activities led to a significant increase in Therapeutic Communication Skills-1 with a large effect size [d: -0.943, 95% CI: (-1.416) (-0.513)], and improved Therapeutic Communication Skills-2 with a large effect size [d: -1.285, 95% CI: (-1.827) - (-0.804)]. Conclusion: The findings indicate that therapeutic activities effectively improved the therapeutic communication skills of nursing students. Practice implications: Integrating therapeutic activities into the Child Health Nursing Course curriculum is recommended to enhance nursing students' therapeutic communication skills.Publication Metadata only The effect of family-centered care education on pediatric nurses' attitudes and clinical practices: nurse and parent perception(W.B. Saunders, 2023) Çetintaş, İsmail; Mutlu, Esra Nur Kocaaslan; Kostak, Melahat Akgün; Dinçkol, Refiye Zafer; Semerci, Remziye; School of NursingBackground and Purpose: Family-centered care (FCC) is a crucial and dynamic philosophy within 21st-century pediatric nursing, offering numerous benefits for both children and their families. It is essential for pediatric nurses to be well-versed in the FCC approach and related practices. The aim of this study is to determine the effect of nurse training on nurses' attitudes towards FCC and on nurses' clinical practices related to FCC. Methods: This study utilized a pretest-posttest, single-blind (for nurses and parents), and prospective design. The sample consisted of nurses (n = 41) employed at a university hospital's pediatric clinics and parents (n = 256) with infants or children admitted to these clinics. Data collection involved the Nurse Information Form, Parent and Child Information Form, Family-Centered Care Scale (FCCS), and Family-Centered Care Attitude Scale (FCCAS). Results: A significant difference was observed between nurses' pre- and post-training FCCAS median scores (p < 0.05). However, no statistically significant difference was detected between the median FCCS scores of parents whose children were cared for by nurses before and after the training (p > 0.05). Conclusion: Following the FCC training provided to pediatric nurses, their attitudes towards the necessity and importance of FCC significantly improved compared to the pre-training period. However, no significant difference was found in the perceived FCC practices of parents whose children received inpatient treatment during the pre-and post-training periods. Implications to practice: Training is important in improving pediatric nurses' attitudes towards FCC. Planned training on FCC should be provided for nurses. Difficulties in pediatric nurses' FCC practices should be identified. In addition, FCC practices should be implemented as a policy in hospitals and pediatric clinics and nurses should be supported to ensure the implementation of FCC practices.Publication Metadata only Prediction of family-centered care on the unmet care needs of parents of pediatric oncology patients and their psychosocial problems(Wiley, 2023) Ay, Ayse; Erkul, Muenevver; Semerci, Remziye; School of NursingBackground/Objectives: It was aimed to determine the predictive power of family-centered care of parents of children with cancer on their unmet care needs and psychosocial problems (anxiety, depression, stress). This study was conducted as a descriptive, correlational, and cross-sectional study. Design/Methods: The study was conducted on 136 parents at a university hospital between January and September 2023, involving parents of children receiving care at the pediatric oncology clinic. Data collection instruments included an Information Form, Family Inventory of Needs Pediatric II (FINPED-II), Family-Centered Care Scale (FCCS), and Depression Anxiety Stress Scale (DASS-21). Data were analyzed using IBM SPSS 28, employing Pearson correlation analysis and linear regression to assess the relationships between variables. Results: The study revealed significant positive correlations between Family-Centered Care and Met Needs (r = .676, p < .001) and significant negative correlations between Met Needs and Stress scores (r = -.256, p < .001). Additionally, there were positive correlations between Anxiety and Depression scores (r = .700, p < .001), Anxiety and Stress scores (r = .768, p < .001), and Depression and Stress scores (r = .835, p < .001). Family-centered care significantly predicted Met Needs (p < .001) and accounted for 47% of the variation in Anxiety, Depression, Stress, and Family Inventory of Needs scores. Conclusion: The findings highlight that family-centered care significantly predicts Met Needs, emphasizing its pivotal role in supporting parents of children with cancer. These findings underscore the importance of family-centered care in pediatric oncology, but also point to the need for further studies to address identified limitations and provide a comprehensive understanding of this complex healthcare dynamic.Publication Metadata only The effect of buzzy and cold spray on pain, anxiety, and fear of children during venipuncture in pediatric emergency department in Turkey; a randomized controlled study(Elsevier Science Inc, 2023) Akarsu, Ozlem; Kilic, Derya; Semerci, Remziye; School of NursingPurpose: It was aimed to evaluate the efficacy of Buzzy and cold spray in reducing pain, anxiety, and fear of children during venipuncture in the emergency department (ED).Methods: This study is an experimental, parallel-group (intervention-control), randomized controlled, single-blind design. The study was conducted with 161 children aged 5-12 years in pediatric ED. Data were collected by the 'Personal Information Form', 'Wong Baker-Facial Expression Rating Scale', 'Child Anxiety Statement Scale', and 'Child Fear Inventory'. Data were analyzed with descriptive statistics, Mann Whitney U test, Kruskal Wallis H test, and Intraclass Correlation.Results: Descriptive features of the children were homogeneous. 'Wong Baker-Facial Expression Rating Scale', 'Child Anxiety Statement Scale', and 'Child Fear Scale' score averages of the children in the control group were higher than the children in the Buzzy group and the cold spray group (p < 0.001). The pain scores of the Buzzy group were higher than those in the cold spray group (p < 0.001). The anxiety and fear mean scores of the children in the Buzzy and cold spray groups were similar (p > 0.05).Conclusion: It was determined that Buzzy and cold spray were more effective than standard care in reducing the level of pain, anxiety, and fear in children ages 5-12 years during venipuncture in the pediatric emergency. The cold spray was more effective in reducing pain than Buzzy.Practice implications: Nurses can use Buzzy and cold sprays to manage the fear, anxiety, and pain associated with venipuncture.Publication Metadata only The effect of an interactive robot on children's post-operative anxiety, mobilization, and parents' satisfaction; randomized controlled study(Elsevier Science Inc, 2023) Topcu, Sacide Yildizeli; Kostak, Melahat Akguen; Guray, Ozlem; Sert, Senem; Yavuz, Gozde; Semerci, Remziye; School of NursingPurpose: To evaluate the effect of an interactive robot on Turkish children's post-operative anxiety, mobilization, and parents' satisfaction related to post-operative care.Method: A randomized controlled study was conducted with 84 children who will undergo day surgery aged 5-10 years and their parents at a university hospital between June 2020-April 2022. The interactive robot was provided to accompany the children during the postoperative mobilization. Children in the control group received standard care during mobilization. Data were collected using the Personal Information Form, Children's State Anxiety (CSA), Parental Satisfaction Scale-Visual Analog Scale, and Mobilization Chart. Results: It was determined that the CSA score of the children in the control group were higher than the intervention group before their first mobilization after surgery (p = 0.005). During the first (p = 0.042) and second (p = 0.012) mobilization, it was determined that the mobilization duration of children in the intervention group was longer than the children in the control group. It was found that the parents of the children in the intervention group had a high level of satisfaction. Conclusion: It has been determined that interactive robots positively affect postoperative mobilization in children undergoing day surgery, reduce the anxiety level of children before mobilization, and increase the duration of mobilization. In addition, the use of interactive robots increased parents' satisfaction with post-operative mobilization care. Practice implications: Using interactive robots to reduce the stress and anxiety of children during the perioperative process can be a promising approach to improve their recovery by providing early mobilization.Publication Metadata only Predicting graft survival in paediatric kidney transplant recipients using machine learning(Springer , 2024) Aksoy, Gulsah Kaya; Akcay, Huseyin Gokhan; Adar, Mehtap; Koyun, Mustafa; Comak, Elif; Akman, Sema; Department of Industrial Engineering; Department of Industrial Engineering; College of EngineeringBackground Identification of factors that affect graft survival in kidney transplantation can increase graft survival and reduce mortality. Artificial intelligence modelling enables impartial evaluation of clinician bias. This study aimed to examine factors that affect the survival of grafts in paediatric kidney transplantation through the use of machine learning. Methods A retrospective review was conducted on records of paediatric patients who underwent kidney transplantation between 1994 and 2021 and had post-transplant follow-up > 12 months. The nearest neighbour method was used to impute missing fields from a total of 48 variables in the dataset. Models including Naive Bayes, logistic regression, support vector machine (SVM), multi-layer perceptron, and XGBoost were trained to predict graft survival. The study used 80% of the patients for training and the remaining 20% for testing. Modelling success was evaluated based on accuracy and F1 score metrics. Results The study analysed 465 kidney transplant recipients. Of these, 56.7% were male. The mean age at transplantation was 12.08 +/- 5.01 years. Of the kidney transplants, 73.1% (n = 339) were from living donors, 34.5% (n = 160) were pre-emptive transplants, and 2.2% (n = 10) were second-time transplants. The machine learning model identified several features associated with graft survival, including antibody-mediated rejection (+ 0.7), acute cellular rejection (+ 0.66), eGFR at 3 years (+ 0.43), eGFR at 5 years (+ 0.34), pre-transplant peritoneal dialysis (+ 0.2), and cadaveric donor (+ 0.2). The successes of the logistic regression and SVM models were similar. The F1 score was 91.9%, and accuracy was 96.5%. Conclusion Machine learning can be used to identify factors that affect graft survival in kidney transplant recipients. By expanding similar studies, risk maps can be created prior to transplantation.Publication Metadata only The effect of 3D modeling on family quality of life, surgical success, and patient outcomes in congenital heart diseases: objectives and design of a randomized controlled trial(Turkish National Pediatric Society, 2024) Sümengen, Aylin Akça; İsmailoğlu, Abdul Veli; İsmailoğlu, Pelin; Çeliker, Alpay; Namlısesli, Deniz; Poyraz, Ezgi; Subaşı, Damla Özçevik; Erdem, Ceren Zeren; Çakır, Gökçe Naz; N/A; Gümüş, Terman; N/A; Koç University HospitalBackground. Understanding the severity of the disease from the parents’ perspective can lead to better patient outcomes, improving both the child’s health-related quality of life and the family’s quality of life. The implementation of 3-dimensional (3D) modeling technology in care is critical from a translational science perspective. Aim. The purpose of this study is to determine the effect of 3D modeling on family quality of life, surgical success, and patient outcomes in congenital heart diseases. Additionally, we aim to identify challenges and potential solutions related to this innovative technology. Methods. The study is a two-group pretest-posttest randomized controlled trial protocol. The sample size is 15 in the experimental group and 15 in the control group. The experimental group’s heart models will be made from their own computed tomography (CT) images and printed using a 3D printer. The experimental group will receive surgical simulation and preoperative parent education with their 3D heart model. The control group will receive the same parent education using the standard anatomical model. Both groups will complete the Sociodemographic Information Form, the Surgical Simulation Evaluation Form-Part I-II, and the Pediatric Quality of Life Inventory (PedsQL) Family Impacts Module. The primary outcome of the research is the average PedsQL Family Impacts Module score. Secondary outcome measurement includes surgical success and patient outcomes. Separate analyses will be conducted for each outcome and compared between the intervention and control groups. Conclusions. Anomalies that can be clearly understood by parents according to the actual size and dimensions of the child’s heart will affect the preoperative preparation of the surgical procedure and the recovery rate in the postoperative period. © 2024, Turkish National Pediatric Society. All rights reserved.