Research Outputs

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    PublicationOpen Access
    1899 yılı Osmanlı İmparatorluğu için jeomekansal ve çok modlu bir ulaşım ağı oluşturma denemesi
    (Koç University Research Center for Anatolian Civilizations (ANAMED) / Koç Üniversitesi Anadolu Medeniyetleri Araştırma Merkezi (ANAMED), 2020) Gerrits, Piet; Department of History; Kabadayı, Mustafa Erdem; Özkan, Osman; Koçak, Turgay; Faculty Member; Teaching Faculty; Department of History; College of Social Sciences and Humanities; 33267; N/A; N/A
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    PublicationOpen Access
    3D-printed contact lenses: challenges towards translation and commercialization
    (Future Medicine, 2022) Yetişen, Ali K.; Department of Mechanical Engineering; Taşoğlu, Savaş; Özdalgıç, Berin; Faculty Member; PhD Student; Department of Mechanical Engineering; KU Arçelik Research Center for Creative Industries (KUAR) / KU Arçelik Yaratıcı Endüstriler Uygulama ve Araştırma Merkezi (KUAR); Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); College of Engineering; Graduate School of Sciences and Engineering; 291971; 323683
    NA
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    PublicationOpen Access
    A case of radiologically isolated syndrome developing Balo's concentric sclerosis lesions on long-term follow-up
    (Elsevier, 2022) Danyeli, Ayça Ersen; Altıntaş, Ayşe; Çalışkan, İlay; Peker, Selçuk; Faculty Member; Faculty Member; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); School of Medicine; Graduate School of Health Sciences; Koç University Hospital; 11611; N/A; N/A; 11480
    Background; Radiologically Isolated Syndrome (RIS) depicts a clinical scenario with multiple sclerosis (MS)-like magnetic resonance imaging (MRI) findings in individuals without clinical features of a demyelinating bout. Balo’s concentric sclerosis (BCS) on the other hand, is a variant of MS characterized by concentrically layered white mater demyelinating lesions. Case presentation: a 49-year-old male with an incidental brain lesion on MRI underwent a stereotactic biopsy and diagnosed as a demyelinating process. He remained asymptomatic throughout the long term clinical and radiological follow-up. However, the patient developed new demyelinating lesions with some showing concentric layers of BCS. Conclusion:this is the first reported case; to our knowledge, whereby a pathologically verified RIS patient developed characteristic BCS lesions. Our case highlights the heterogeneity of RIS as a clinico-radiological entity, requiring further sub-classification of the spectrum for improved management
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    PublicationOpen Access
    A community-based approach to prevention of pressure injuries: a study of the European Wound Management Association Research Grant
    (European Wound Management Association (EWMA), 2021) Karadağ, Ayişe; Çakar, Vildan; Faculty Member; School of Medicine; Graduate School of Health Sciences; 3549; N/A
    Pressure injuries (PIs) are important health problems all over the world because of their serious effects. Awareness of PIs and their effects has increased in recent years. Since patients’ relatives are part of the care team, they have an important role to play in the prevention of PIs. The most crucial aspect of the prevention of PIs is the education of healthcare professionals, patients and patients’ relatives and caregivers. This study aimed to educate caregivers on the prevention of PIs through the development of a digital game. With this purpose, we developed and used a technological education approach —a digital game— that employs gamification methods
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    PublicationOpen Access
    A preliminary attempt to construct a geospatial, multimodal Ottoman transport network for 1899
    (Koç University Press (KUP) / Koç Üniversitesi Yayınları (KÜY), 2021) Gerrits, Piet; Department of History; Kabadayı, Mustafa Erdem; Özkan, Osman; Koçak, Turgay; Faculty Member; Teaching Faculty; Department of History; College of Social Sciences and Humanities; 33267; N/A; N/A
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    PublicationOpen Access
    A wearable paper-integrated microfluidic device for sequential analysis of sweat based on capillary action
    (Royal Society of Chemistry (RSC), 2022) Koydemir, Hatice Ceylan; Department of Mechanical Engineering; Department of Electrical and Electronics Engineering; Beker, Levent; Abbasiasl, Taher; Mirlou, Fariborz; İstif, Emin; Faculty Member; Department of Mechanical Engineering; Department of Electrical and Electronics Engineering; College of Engineering; Graduate School of Sciences and Engineering; 308798; N/A; N/A; N/A
    Soft, skin-mounted microfluidic devices can collect microliter volumes of eccrine sweat and are capable of in situ real-time analysis of different biomarkers to assess physiological state and health. Chrono-analysis of sweat can be implemented to monitor temporal variations of biomarker concentrations over a certain period of interest. Conventional methods used to capture sweat or some of the newly developed microfluidic platforms for sweat collection and analysis are based on absorbent pads. They suffer from evaporation, leading to considerable deviations in the concentration of the biomarkers. Here, a paperintegrated microfluidic device is presented for sequential analysis of sweat that is easy to fabricate and does not include air exits for each reservoir, which reduces undesirable effects of sweat evaporation. Furthermore, the high capillary force of filter paper is leveraged to route the liquid into the chambers in a sequential fashion and allow further chemical analysis. The employed design of the paper-embedded microfluidic device successfully samples and analyzes artificial sweat sequentially for flow rates up to 5 ?L min?1 without showing any leakage. We demonstrated the performance of the device, employing colorimetric assays for chrono-analysis of glucose standard solutions at concentrations in the range of 10– 100 mM and pH of sweat during exercise. The results reveal the presented approach's functionality and potential to analyze the concentration of biomarkers over a certain period sequentially.
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    PublicationOpen Access
    An historical geographic information system for Ottoman Studies. The c. 1907 Ottoman Census and Armenian Settlement in Istanbul
    (Peeters Online Journals, 2020) Ohanian, Daniel; Başkurt, Z. Mehmet; Department of History; Kabadayı, Mustafa Erdem; Faculty Member; Department of History; College of Social Sciences and Humanities; 33267
    The purpose of this article is to announce the publication of a partial transcription of the c. 1907 Ottoman census that relates to 24,000 Apostolic Armenian Istanbulites and of a historical geographic information system (HGIS), or interactive map, that shows where these individuals lived. Within this framework, the authors first present their argument that an unidentified, microfilmed population register housed in New York is the most substantial portion of this census currently available to researchers. In the second part of their article, they introduce HGISes as tools for the digital humanities and describe the process of creating one.
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    PublicationOpen Access
    An improved lower bound on the competitive ratio of deterministic online algorithms for the multi-agent k-Canadian Traveler Problem
    (Finding Press, 2022) Shiri, Davood; Department of Industrial Engineering; Salman, Fatma Sibel; Faculty Member; Department of Industrial Engineering; College of Engineering; 178838
    We present an improved lower bound on the competitive ratio of deterministic online algorithms for the multi-agent k-Canadian Traveler Problem.
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    PublicationOpen Access
    Artificial eye model and holographic display based IOL simulator
    (Society of Photo-optical Instrumentation Engineers (SPIE), 2023) N/A; Department of Electrical and Electronics Engineering; N/A; Şahin, Afsun; Ürey, Hakan; Aygün, Uğur; Kavaklı, Koray; Akyazı, Deniz; Faculty Member; Faculty Member; Department of Electrical and Electronics Engineering; School of Medicine; College of Engineering; Graduate School of Sciences and Engineering; 171267; 8579; N/A; N/A; N/A
    Cataract is a common ophthalmic disease in which a cloudy area is formed in the lens of the eye and requires surgical removal and replacement of eye lens. Careful selection of the intraocular lens (IOL) is critical for the post-surgery satisfaction of the patient. Although there are various types of IOLs in the market with different properties, it is challenging for the patient to imagine how they will perceive the world after the surgery. We propose a novel holographic vision simulator which utilizes non-cataractous regions on eye lens to allow the cataract patients to experience post-operative visual acuity before surgery. Computer generated holography display technology enables to shape and steer the light beam through the relatively clear areas of the patient’s lens. Another challenge for cataract surgeries is to match the right patient with the right IOL. To evaluate various IOLs, we developed an artificial human eye composed of a scleral lens, a glass retina, an iris, and a replaceable IOL holder. Next, we tested different IOLs (monofocal and multifocal) by capturing real-world scenes to demonstrate visual artifacts. Then, the artificial eye was implemented in the benchtop holographic simulator to evaluate various IOLs using different light sources and holographic contents.
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    PublicationOpen Access
    Being able to be mother: traditional practices of women in coping with infertility in Melekli Town of Iğdır
    (2022) Çetinkaya Şimşek, Şahika; Eroğlu, Kafiye; Faculty Member; School of Nursing; 6061
    Numerous traditional methods are used in the treatment of infertility around the world. The study of aim is to investigate the knowledge and experience of traditional methods by women to find solutions to infertility in Melekli Town in Iğdır. The research is a descriptive and cross-sectional study. The minimum sample size of the study was determined according to the formula of the incidence of the event in cases with a known population. The research was carried out with 214 women using face-to-face interview method in a town in the easternmost part of Turkey. The data were collected with a pen and ended questions form during the home visits to determine the socio-demographic characteristics of the women and their knowledge and experiences about the methods. The interviews lasted between 30- 45 minutes. Of the responding women, 85% had known traditional practice, and 9.3% had tried traditional methods. The traditional methods known by women to get pregnant were sitting on the vapor, intravaginal applications, vaginal application through the pad, applying heat in the abdominal area, drinking a mixture, wrapping the pelvic area. Having children is significantly affected the use of traditional practices (P < 0.05). Almost all the women participating in the study stated that they knew the traditional method to have children, and very few of them applied the traditional methods they knew to have children. / Dünyada infertilite tedavisinde çok sayıda geleneksel yöntem kullanılmaktadır. Bu çalışmanın amacı, Iğdır Melekli kasabasında yaşayan kadınların infertiliteye çözüm bulmak için kadınların geleneksel yöntemlerle ilgili bilgi ve deneyimlerini araştırmaktır. Araştırma tanımlayıcı ve kesitsel bir çalışmadır. Araştırmanın minimum örneklem büyüklüğü, popülasyonu bilinen olgularda olayın görülme sıklığı formülüne göre belirlenmiştir. Araştırma Türkiye’nin en doğusundaki yer alan Iğdır’ın Melekli kasabasında yüz yüze görüşme yöntemi kullanılarak 214 kadınla gerçekleştirilmiştir. Veriler, ev ziyaretleri sırasında kadınların sosyo-demografik özellikleri ve yöntemlere ilişkin bilgi ve deneyimlerini belirlemek için açık ve kapalı uçlu sorulardan oluşan form ile toplanmıştır. Görüşmeler 30-45 dakika arasında sürmüştür. Yanıt veren kadınların %85’i çocuk sahibi olabilmek için geleneksel yöntemleri bildiklerini ve %9,3’ü ise gebe kalmak için geleneksel yöntemleri denediğini belirtmiştir. Kadınların gebe kalmak için sıklıkla bildikleri geleneksel yöntemler; buhar üzerine oturma, doğrudan vajen içine yapılan uygulamalar, ped aracılığıyla yapılan vajinal uygulamalar, karın bölgesine ısı uygulama, karışım içme, pelvik bölgeyi sarma şeklindedir. Çocuk sahibi olmak için geleneksel uygulamaların kullanımını önemli ölçüde etkilemektedir (P<0.05). Çalışmaya katılan kadınların neredeyse tamamı çocuk sahibi olabilmek için geleneksel yöntemleri bildiğini ve çok az kısmı ise çocuk sahibi olmak için bildikleri geleneksel yöntemleri uyguladığını belirtmiştir.